ATF3.H12RSNP.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12RSNP.2.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	GRTGAYGYAAYh
GC content	46.95%
Information content (bits; total / per base)	13.995 / 1.166
Data sources	ChIP-Seq
Aligned words	653

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.743	0.97	0.676	0.932	0.725	0.965	2.514	5.003	131.554	758.495
Mouse	13 (85)	0.848	0.874	0.719	0.772	0.818	0.843	2.493	2.833	137.284	237.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.999	0.998	0.999	0.998	0.996	0.995
Overall, 4 experiments	best	0.999	0.998	0.999	0.998	0.999	0.998
Methyl HT-SELEX, 2 experiments	median	0.999	0.997	0.998	0.996	0.994	0.992
Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.999	0.998	0.996	0.994
Non-Methyl HT-SELEX, 2 experiments	median	0.999	0.998	0.999	0.998	0.998	0.996
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.999	0.998	0.999	0.998

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.623	6.288	0.132	0.127

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.756	0.445	0.788	0.522
batch 2	0.823	0.66	0.743	0.542

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12RSNP.2.P.B.pcm
PWM	ATF3.H12RSNP.2.P.B.pwm
PFM	ATF3.H12RSNP.2.P.B.pfm
Alignment	ATF3.H12RSNP.2.P.B.words.tsv
Threshold to P-value map	ATF3.H12RSNP.2.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12RSNP.2.P.B_jaspar_format.txt
MEME format	ATF3.H12RSNP.2.P.B_meme_format.meme
Transfac format	ATF3.H12RSNP.2.P.B_transfac_format.txt
Homer format	ATF3.H12RSNP.2.P.B_homer_format_0.001.txt ATF3.H12RSNP.2.P.B_homer_format_0.0005.txt ATF3.H12RSNP.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	81.0	23.0	542.0	7.0
02	453.0	23.0	176.0	1.0
03	0.0	0.0	0.0	653.0
04	0.0	0.0	653.0	0.0
05	653.0	0.0	0.0	0.0
06	1.0	378.0	1.0	273.0
07	0.0	0.0	504.0	149.0
08	16.0	370.0	0.0	267.0
09	438.0	215.0	0.0	0.0
10	517.0	39.0	12.0	85.0
11	4.0	288.0	76.0	285.0
12	157.0	295.0	84.0	117.0

PFM

	A	C	G	T
01	0.124	0.035	0.83	0.011
02	0.694	0.035	0.27	0.002
03	0.0	0.0	0.0	1.0
04	0.0	0.0	1.0	0.0
05	1.0	0.0	0.0	0.0
06	0.002	0.579	0.002	0.418
07	0.0	0.0	0.772	0.228
08	0.025	0.567	0.0	0.409
09	0.671	0.329	0.0	0.0
10	0.792	0.06	0.018	0.13
11	0.006	0.441	0.116	0.436
12	0.24	0.452	0.129	0.179

PWM

	A	C	G	T
01	-0.691	-1.902	1.193	-2.951
02	1.014	-1.902	0.074	-4.142
03	-4.622	-4.622	-4.622	1.379
04	-4.622	-4.622	1.379	-4.622
05	1.379	-4.622	-4.622	-4.622
06	-4.142	0.834	-4.142	0.51
07	-4.622	-4.622	1.121	-0.09
08	-2.236	0.813	-4.622	0.488
09	0.981	0.273	-4.622	-4.622
10	1.146	-1.401	-2.494	-0.644
11	-3.379	0.563	-0.753	0.553
12	-0.039	0.587	-0.655	-0.329

Standard thresholds

P-value	Threshold
0.001	2.784465
0.0005	4.13813
0.0001	6.98258