ATF3.H12RSNP.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12RSNP.1.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	10
Consensus	dRTGACKYvd
GC content	52.71%
Information content (bits; total / per base)	8.674 / 0.867
Data sources	ChIP-Seq
Aligned words	1003

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.813	0.916	0.703	0.855	0.777	0.889	2.365	3.279	157.495	549.523
Mouse	13 (85)	0.844	0.866	0.695	0.76	0.766	0.797	1.997	2.355	115.125	159.602

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.995	0.997	0.994	0.99	0.986
Overall, 4 experiments	best	0.998	0.996	0.998	0.997	0.998	0.996
Methyl HT-SELEX, 2 experiments	median	0.995	0.991	0.991	0.985	0.98	0.971
Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.995	0.992	0.984	0.978
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.996	0.998	0.996	0.997	0.995
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.996	0.998	0.997	0.998	0.996

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.059	5.112	0.091	0.103

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.774	0.466	0.76	0.497
batch 2	0.855	0.681	0.76	0.562

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12RSNP.1.P.B.pcm
PWM	ATF3.H12RSNP.1.P.B.pwm
PFM	ATF3.H12RSNP.1.P.B.pfm
Alignment	ATF3.H12RSNP.1.P.B.words.tsv
Threshold to P-value map	ATF3.H12RSNP.1.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12RSNP.1.P.B_jaspar_format.txt
MEME format	ATF3.H12RSNP.1.P.B_meme_format.meme
Transfac format	ATF3.H12RSNP.1.P.B_transfac_format.txt
Homer format	ATF3.H12RSNP.1.P.B_homer_format_0.001.txt ATF3.H12RSNP.1.P.B_homer_format_0.0005.txt ATF3.H12RSNP.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	235.0	100.0	509.0	159.0
02	299.0	49.0	647.0	8.0
03	12.0	14.0	13.0	964.0
04	4.0	283.0	706.0	10.0
05	890.0	10.0	86.0	17.0
06	13.0	826.0	9.0	155.0
07	36.0	9.0	732.0	226.0
08	44.0	405.0	8.0	546.0
09	453.0	196.0	321.0	33.0
10	510.0	115.0	249.0	129.0

PFM

	A	C	G	T
01	0.234	0.1	0.507	0.159
02	0.298	0.049	0.645	0.008
03	0.012	0.014	0.013	0.961
04	0.004	0.282	0.704	0.01
05	0.887	0.01	0.086	0.017
06	0.013	0.824	0.009	0.155
07	0.036	0.009	0.73	0.225
08	0.044	0.404	0.008	0.544
09	0.452	0.195	0.32	0.033
10	0.508	0.115	0.248	0.129

PWM

	A	C	G	T
01	-0.064	-0.909	0.705	-0.452
02	0.175	-1.605	0.944	-3.256
03	-2.912	-2.776	-2.842	1.342
04	-3.786	0.12	1.031	-3.069
05	1.262	-3.069	-1.057	-2.601
06	-2.842	1.187	-3.158	-0.477
07	-1.901	-3.158	1.067	-0.103
08	-1.709	0.477	-3.256	0.774
09	0.588	-0.244	0.245	-1.984
10	0.706	-0.771	-0.007	-0.658

Standard thresholds

P-value	Threshold
0.001	5.052415
0.0005	5.855285
0.0001	7.293965