ATF3.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12RSNP.0.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	nvvTGACTCA
GC content	48.09%
Information content (bits; total / per base)	11.548 / 1.155
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.72	0.915	0.629	0.865	0.707	0.907	2.26	3.721	82.935	298.022
Mouse	13 (85)	0.867	0.912	0.8	0.853	0.849	0.902	3.077	3.603	174.638	246.569

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.927	0.898	0.902	0.858	0.878	0.827
Overall, 4 experiments	best	0.991	0.986	0.96	0.949	0.907	0.886
Methyl HT-SELEX, 2 experiments	median	0.967	0.954	0.929	0.906	0.889	0.854
Methyl HT-SELEX, 2 experiments	best	0.991	0.986	0.96	0.949	0.907	0.886
Non-Methyl HT-SELEX, 2 experiments	median	0.901	0.861	0.9	0.844	0.878	0.821
Non-Methyl HT-SELEX, 2 experiments	best	0.911	0.872	0.906	0.854	0.885	0.83

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.985	2.316	0.05	0.09

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.735	0.34	0.621	0.388
batch 2	0.714	0.391	0.505	0.39

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12RSNP.0.P.B.pcm
PWM	ATF3.H12RSNP.0.P.B.pwm
PFM	ATF3.H12RSNP.0.P.B.pfm
Alignment	ATF3.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	ATF3.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12RSNP.0.P.B_jaspar_format.txt
MEME format	ATF3.H12RSNP.0.P.B_meme_format.meme
Transfac format	ATF3.H12RSNP.0.P.B_transfac_format.txt
Homer format	ATF3.H12RSNP.0.P.B_homer_format_0.001.txt ATF3.H12RSNP.0.P.B_homer_format_0.0005.txt ATF3.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	205.0	244.0	314.0	237.0
02	193.0	186.0	501.0	120.0
03	393.0	214.0	380.0	13.0
04	0.0	2.0	7.0	991.0
05	3.0	9.0	972.0	16.0
06	974.0	8.0	8.0	10.0
07	2.0	856.0	2.0	140.0
08	20.0	0.0	172.0	808.0
09	68.0	865.0	14.0	53.0
10	941.0	46.0	9.0	4.0

PFM

	A	C	G	T
01	0.205	0.244	0.314	0.237
02	0.193	0.186	0.501	0.12
03	0.393	0.214	0.38	0.013
04	0.0	0.002	0.007	0.991
05	0.003	0.009	0.972	0.016
06	0.974	0.008	0.008	0.01
07	0.002	0.856	0.002	0.14
08	0.02	0.0	0.172	0.808
09	0.068	0.865	0.014	0.053
10	0.941	0.046	0.009	0.004

PWM

	A	C	G	T
01	-0.197	-0.024	0.227	-0.053
02	-0.257	-0.293	0.692	-0.727
03	0.45	-0.154	0.416	-2.839
04	-4.982	-4.213	-3.362	1.372
05	-3.975	-3.156	1.353	-2.653
06	1.355	-3.253	-3.253	-3.066
07	-4.213	1.226	-4.213	-0.574
08	-2.45	-4.982	-0.371	1.168
09	-1.284	1.236	-2.773	-1.526
10	1.32	-1.663	-3.156	-3.783

Standard thresholds

P-value	Threshold
0.001	4.22187
0.0005	5.18995
0.0001	7.405015