ATF3.H12INVIVO.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12INVIVO.2.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	11
Consensus	RRTGAYKYAWb
GC content	46.0%
Information content (bits; total / per base)	11.239 / 1.022
Data sources	ChIP-Seq
Aligned words	958

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.754	0.976	0.671	0.94	0.745	0.974	2.539	4.72	140.148	786.143
Mouse	13 (85)	0.883	0.903	0.763	0.809	0.846	0.871	2.582	2.927	174.432	267.721

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.998	0.996	0.998	0.996	0.996	0.994
Overall, 4 experiments	best	0.999	0.997	0.999	0.998	0.998	0.997
Methyl HT-SELEX, 2 experiments	median	0.998	0.995	0.997	0.994	0.994	0.99
Methyl HT-SELEX, 2 experiments	best	0.998	0.996	0.998	0.996	0.995	0.993
Non-Methyl HT-SELEX, 2 experiments	median	0.999	0.997	0.999	0.997	0.998	0.996
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.997	0.999	0.998	0.998	0.997

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.172	5.385	0.127	0.133

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.788	0.438	0.791	0.504
batch 2	0.829	0.643	0.751	0.565

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12INVIVO.2.P.B.pcm
PWM	ATF3.H12INVIVO.2.P.B.pwm
PFM	ATF3.H12INVIVO.2.P.B.pfm
Alignment	ATF3.H12INVIVO.2.P.B.words.tsv
Threshold to P-value map	ATF3.H12INVIVO.2.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12INVIVO.2.P.B_jaspar_format.txt
MEME format	ATF3.H12INVIVO.2.P.B_meme_format.meme
Transfac format	ATF3.H12INVIVO.2.P.B_transfac_format.txt
Homer format	ATF3.H12INVIVO.2.P.B_homer_format_0.001.txt ATF3.H12INVIVO.2.P.B_homer_format_0.0005.txt ATF3.H12INVIVO.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	158.0	104.0	613.0	83.0
02	608.0	81.0	264.0	5.0
03	6.0	4.0	3.0	945.0
04	0.0	9.0	941.0	8.0
05	938.0	8.0	6.0	6.0
06	5.0	618.0	25.0	310.0
07	16.0	13.0	593.0	336.0
08	37.0	582.0	9.0	330.0
09	653.0	297.0	6.0	2.0
10	628.0	99.0	40.0	191.0
11	71.0	403.0	130.0	354.0

PFM

	A	C	G	T
01	0.165	0.109	0.64	0.087
02	0.635	0.085	0.276	0.005
03	0.006	0.004	0.003	0.986
04	0.0	0.009	0.982	0.008
05	0.979	0.008	0.006	0.006
06	0.005	0.645	0.026	0.324
07	0.017	0.014	0.619	0.351
08	0.039	0.608	0.009	0.344
09	0.682	0.31	0.006	0.002
10	0.656	0.103	0.042	0.199
11	0.074	0.421	0.136	0.37

PWM

	A	C	G	T
01	-0.412	-0.825	0.935	-1.046
02	0.927	-1.07	0.097	-3.581
03	-3.442	-3.742	-3.935	1.367
04	-4.946	-3.114	1.363	-3.212
05	1.36	-3.212	-3.442	-3.442
06	-3.581	0.944	-2.2	0.256
07	-2.611	-2.797	0.902	0.337
08	-1.829	0.884	-3.114	0.319
09	0.999	0.214	-3.442	-4.173
10	0.96	-0.873	-1.755	-0.224
11	-1.199	0.517	-0.605	0.388

Standard thresholds

P-value	Threshold
0.001	4.304415
0.0005	5.38342
0.0001	7.496675