ATF3.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12INVIVO.1.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	dRTGACKYvvb
GC content	53.68%
Information content (bits; total / per base)	8.766 / 0.797
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.823	0.934	0.719	0.853	0.789	0.911	2.546	3.465	168.923	616.018
Mouse	13 (85)	0.851	0.875	0.713	0.78	0.77	0.806	2.06	2.425	123.678	173.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.994	0.996	0.993	0.99	0.985
Overall, 4 experiments	best	0.998	0.996	0.998	0.996	0.997	0.995
Methyl HT-SELEX, 2 experiments	median	0.995	0.989	0.991	0.985	0.98	0.971
Methyl HT-SELEX, 2 experiments	best	0.997	0.993	0.995	0.99	0.985	0.978
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.995	0.998	0.996	0.996	0.994
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.996	0.998	0.996	0.997	0.995

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.331	5.633	0.074	0.106

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.772	0.446	0.753	0.5
batch 2	0.835	0.659	0.717	0.537

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12INVIVO.1.P.B.pcm
PWM	ATF3.H12INVIVO.1.P.B.pwm
PFM	ATF3.H12INVIVO.1.P.B.pfm
Alignment	ATF3.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	ATF3.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	ATF3.H12INVIVO.1.P.B_meme_format.meme
Transfac format	ATF3.H12INVIVO.1.P.B_transfac_format.txt
Homer format	ATF3.H12INVIVO.1.P.B_homer_format_0.001.txt ATF3.H12INVIVO.1.P.B_homer_format_0.0005.txt ATF3.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	215.0	122.0	530.0	134.0
02	301.0	59.0	630.0	11.0
03	20.0	6.0	13.0	962.0
04	12.0	276.0	706.0	7.0
05	893.0	13.0	90.0	5.0
06	5.0	795.0	11.0	190.0
07	20.0	16.0	734.0	231.0
08	30.0	466.0	7.0	498.0
09	474.0	162.0	333.0	32.0
10	478.0	135.0	258.0	130.0
11	138.0	347.0	202.0	314.0

PFM

	A	C	G	T
01	0.215	0.122	0.529	0.134
02	0.301	0.059	0.629	0.011
03	0.02	0.006	0.013	0.961
04	0.012	0.276	0.705	0.007
05	0.892	0.013	0.09	0.005
06	0.005	0.794	0.011	0.19
07	0.02	0.016	0.733	0.231
08	0.03	0.466	0.007	0.498
09	0.474	0.162	0.333	0.032
10	0.478	0.135	0.258	0.13
11	0.138	0.347	0.202	0.314

PWM

	A	C	G	T
01	-0.151	-0.711	0.747	-0.619
02	0.183	-1.423	0.919	-2.986
03	-2.451	-3.485	-2.84	1.341
04	-2.91	0.097	1.033	-3.363
05	1.267	-2.84	-1.011	-3.623
06	-3.623	1.151	-2.986	-0.273
07	-2.451	-2.654	1.072	-0.079
08	-2.072	0.619	-3.363	0.685
09	0.636	-0.431	0.284	-2.011
10	0.644	-0.611	0.03	-0.649
11	-0.59	0.325	-0.213	0.226

Standard thresholds

P-value	Threshold
0.001	5.05035
0.0005	5.86919
0.0001	7.30668