ATF3.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF3.H12INVIVO.0.P.B
Gene (human)	ATF3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	dRTGAYKCAh
GC content	43.41%
Information content (bits; total / per base)	10.89 / 1.089
Data sources	ChIP-Seq
Aligned words	1002

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	18 (118)	0.734	0.911	0.668	0.857	0.737	0.895	2.472	3.467	100.864	371.886
Mouse	13 (85)	0.882	0.91	0.804	0.849	0.863	0.896	2.982	3.344	186.921	283.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.933	0.91	0.897	0.856	0.839	0.796
Overall, 4 experiments	best	0.991	0.984	0.961	0.951	0.894	0.878
Methyl HT-SELEX, 2 experiments	median	0.971	0.959	0.93	0.908	0.856	0.834
Methyl HT-SELEX, 2 experiments	best	0.991	0.984	0.961	0.951	0.894	0.878
Non-Methyl HT-SELEX, 2 experiments	median	0.906	0.878	0.895	0.845	0.839	0.796
Non-Methyl HT-SELEX, 2 experiments	best	0.915	0.886	0.897	0.846	0.839	0.796

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.267	3.153	0.055	0.092

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.677	0.29	0.545	0.346
batch 2	0.567	0.224	0.28	0.277

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	ATF3-like {1.1.2.2} (TFClass)
TFClass ID	TFClass: 1.1.2.2.1
HGNC	HGNC:785
MGI	MGI:109384
EntrezGene (human)	GeneID:467 (SSTAR profile)
EntrezGene (mouse)	GeneID:11910 (SSTAR profile)
UniProt ID (human)	ATF3_HUMAN
UniProt ID (mouse)	ATF3_MOUSE
UniProt AC (human)	P18847 (TFClass)
UniProt AC (mouse)	Q60765 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	18 human, 13 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF3.H12INVIVO.0.P.B.pcm
PWM	ATF3.H12INVIVO.0.P.B.pwm
PFM	ATF3.H12INVIVO.0.P.B.pfm
Alignment	ATF3.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	ATF3.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ATF3.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	ATF3.H12INVIVO.0.P.B_meme_format.meme
Transfac format	ATF3.H12INVIVO.0.P.B_transfac_format.txt
Homer format	ATF3.H12INVIVO.0.P.B_homer_format_0.001.txt ATF3.H12INVIVO.0.P.B_homer_format_0.0005.txt ATF3.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	256.0	131.0	459.0	156.0
02	491.0	192.0	318.0	1.0
03	3.0	0.0	4.0	995.0
04	3.0	4.0	979.0	16.0
05	961.0	5.0	30.0	6.0
06	8.0	649.0	31.0	314.0
07	38.0	20.0	306.0	638.0
08	127.0	843.0	11.0	21.0
09	977.0	12.0	2.0	11.0
10	374.0	231.0	123.0	274.0

PFM

	A	C	G	T
01	0.255	0.131	0.458	0.156
02	0.49	0.192	0.317	0.001
03	0.003	0.0	0.004	0.993
04	0.003	0.004	0.977	0.016
05	0.959	0.005	0.03	0.006
06	0.008	0.648	0.031	0.313
07	0.038	0.02	0.305	0.637
08	0.127	0.841	0.011	0.021
09	0.975	0.012	0.002	0.011
10	0.373	0.231	0.123	0.273

PWM

	A	C	G	T
01	0.022	-0.642	0.602	-0.469
02	0.67	-0.264	0.237	-4.527
03	-3.977	-4.984	-3.785	1.374
04	-3.977	-3.785	1.358	-2.655
05	1.339	-3.624	-2.073	-3.486
06	-3.255	0.948	-2.042	0.225
07	-1.848	-2.452	0.199	0.931
08	-0.673	1.209	-2.987	-2.407
09	1.356	-2.911	-4.215	-2.987
10	0.399	-0.08	-0.704	0.089

Standard thresholds

P-value	Threshold
0.001	4.3694
0.0005	5.34746
0.0001	7.75654