MotifATF3.H12INVITRO.3.SM.B
Gene (human)ATF3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Atf3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length15
ConsensusnvbKATGACGTCAYn
GC content46.64%
Information content (bits; total / per base)17.147 / 1.143
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2272

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 18 (118) 0.654 0.86 0.541 0.788 0.592 0.835 1.815 4.065 65.909 392.538
Mouse 13 (85) 0.744 0.775 0.607 0.69 0.698 0.727 2.11 2.835 64.319 99.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 1.0 1.0 1.0 1.0 0.999 0.999
best 1.0 1.0 1.0 1.0 1.0 0.999
Methyl HT-SELEX, 2 experiments median 1.0 1.0 1.0 0.999 0.999 0.998
best 1.0 1.0 1.0 1.0 0.999 0.999
Non-Methyl HT-SELEX, 2 experiments median 1.0 1.0 1.0 1.0 1.0 0.999
best 1.0 1.0 1.0 1.0 1.0 0.999

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.829 8.629 0.135 0.129

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.831 0.517 0.737 0.482
batch 2 0.868 0.694 0.835 0.65
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyFos-related {1.1.2} (TFClass)
TF subfamilyATF3-like {1.1.2.2} (TFClass)
TFClass IDTFClass: 1.1.2.2.1
HGNCHGNC:785
MGIMGI:109384
EntrezGene (human)GeneID:467
(SSTAR profile)
EntrezGene (mouse)GeneID:11910
(SSTAR profile)
UniProt ID (human)ATF3_HUMAN
UniProt ID (mouse)ATF3_MOUSE
UniProt AC (human)P18847
(TFClass)
UniProt AC (mouse)Q60765
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 18 human, 13 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01669.5550.5675.5376.5
02799.5474.5776.5221.5
03192.0566.0291.01223.0
04211.073.01725.0263.0
051923.028.0321.00.0
060.06.02.02264.0
070.00.02247.025.0
082272.00.00.00.0
090.01999.02.0271.0
10376.015.01879.02.0
113.05.01.02263.0
12250.01998.013.011.0
132217.011.034.010.0
1431.75769.75204.751265.75
15418.75807.75419.75625.75
PFM
ACGT
010.2950.2420.2970.166
020.3520.2090.3420.097
030.0850.2490.1280.538
040.0930.0320.7590.116
050.8460.0120.1410.0
060.00.0030.0010.996
070.00.00.9890.011
081.00.00.00.0
090.00.880.0010.119
100.1650.0070.8270.001
110.0010.0020.00.996
120.110.8790.0060.005
130.9760.0050.0150.004
140.0140.3390.090.557
150.1840.3560.1850.275
PWM
ACGT
010.164-0.0310.173-0.409
020.341-0.1790.312-0.936
03-1.078-0.004-0.6660.765
04-0.985-2.0291.109-0.766
051.217-2.947-0.568-5.687
06-5.687-4.275-4.9761.38
07-5.687-5.6871.373-3.052
081.384-5.687-5.687-5.687
09-5.6871.256-4.976-0.736
10-0.411-3.5161.194-4.976
11-4.75-4.409-5.271.38
12-0.8161.255-3.642-3.786
131.359-3.786-2.764-3.866
14-2.8290.303-1.0140.799
15-0.3040.351-0.3010.097
Standard thresholds
P-value Threshold
0.001 0.31996
0.0005 1.94946
0.0001 5.28406