MotifATF2.H12INVIVO.1.P.B
Gene (human)ATF2
(GeneCards)
Gene synonyms (human)CREB2, CREBP1
Gene (mouse)Atf2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusdATGAYGTCATn
GC content37.43%
Information content (bits; total / per base)15.6 / 1.3
Data sourcesChIP-Seq
Aligned words976

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.978 0.995 0.929 0.978 0.989 0.998 6.042 7.19 799.036 1208.638
Mouse 2 (12) 0.818 0.884 0.743 0.827 0.802 0.866 3.229 3.708 202.244 257.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.971 0.955 0.929 0.906 0.835 0.818
best 0.997 0.995 0.989 0.984 0.93 0.925
Methyl HT-SELEX, 2 experiments median 0.99 0.984 0.969 0.959 0.893 0.884
best 0.997 0.995 0.989 0.984 0.93 0.925
Non-Methyl HT-SELEX, 2 experiments median 0.944 0.914 0.892 0.857 0.8 0.775
best 0.959 0.936 0.908 0.879 0.813 0.792

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.826 10.46 0.216 0.23

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.754 0.394 0.667 0.435
batch 2 0.816 0.628 0.728 0.526
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyJun-related {1.1.1} (TFClass)
TF subfamilyATF2 {1.1.1.3} (TFClass)
TFClass IDTFClass: 1.1.1.3.1
HGNCHGNC:784
MGIMGI:109349
EntrezGene (human)GeneID:1386
(SSTAR profile)
EntrezGene (mouse)GeneID:11909
(SSTAR profile)
UniProt ID (human)ATF2_HUMAN
UniProt ID (mouse)ATF2_MOUSE
UniProt AC (human)P15336
(TFClass)
UniProt AC (mouse)P16951
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01359.0106.0354.0157.0
02763.04.0193.016.0
035.09.04.0958.0
0410.03.0943.020.0
05964.03.07.02.0
067.0244.049.0676.0
073.02.0964.07.0
0815.09.01.0951.0
09156.0806.010.04.0
10956.02.010.08.0
115.0107.058.0806.0
12199.0341.0155.0281.0
PFM
ACGT
010.3680.1090.3630.161
020.7820.0040.1980.016
030.0050.0090.0040.982
040.010.0030.9660.02
050.9880.0030.0070.002
060.0070.250.050.693
070.0030.0020.9880.007
080.0150.0090.0010.974
090.160.8260.010.004
100.980.0020.010.008
110.0050.110.0590.826
120.2040.3490.1590.288
PWM
ACGT
010.384-0.8250.37-0.437
021.135-3.76-0.233-2.629
03-3.599-3.132-3.761.362
04-3.043-3.9521.347-2.426
051.369-3.952-3.338-4.19
06-3.3380.0-1.5781.015
07-3.952-4.191.369-3.338
08-2.688-3.132-4.5031.355
09-0.4431.19-3.043-3.76
101.36-4.19-3.043-3.23
11-3.599-0.815-1.4151.19
12-0.2020.333-0.450.14
Standard thresholds
P-value Threshold
0.001 2.12321
0.0005 3.429715
0.0001 6.264195