Motif | ATF2.H12INVIVO.0.PSM.A |
Gene (human) | ATF2 (GeneCards) |
Gene synonyms (human) | CREB2, CREBP1 |
Gene (mouse) | Atf2 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | ATF2.H12INVIVO.0.PSM.A |
Gene (human) | ATF2 (GeneCards) |
Gene synonyms (human) | CREB2, CREBP1 |
Gene (mouse) | Atf2 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 11 |
Consensus | nRTGAYGTCAY |
GC content | 44.69% |
Information content (bits; total / per base) | 15.126 / 1.375 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 981 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 5 (35) | 0.984 | 0.996 | 0.946 | 0.984 | 0.992 | 0.999 | 6.699 | 7.875 | 811.237 | 1230.921 |
Mouse | 2 (12) | 0.84 | 0.905 | 0.772 | 0.863 | 0.816 | 0.884 | 3.437 | 4.197 | 228.974 | 288.553 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.978 | 0.965 | 0.942 | 0.922 | 0.848 | 0.834 |
best | 0.997 | 0.995 | 0.989 | 0.985 | 0.929 | 0.924 | |
Methyl HT-SELEX, 2 experiments | median | 0.991 | 0.985 | 0.971 | 0.961 | 0.894 | 0.886 |
best | 0.997 | 0.995 | 0.989 | 0.985 | 0.929 | 0.924 | |
Non-Methyl HT-SELEX, 2 experiments | median | 0.959 | 0.936 | 0.916 | 0.886 | 0.824 | 0.803 |
best | 0.971 | 0.954 | 0.93 | 0.906 | 0.836 | 0.819 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 28.563 | 57.113 | 0.341 | 0.343 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.836 | 0.58 | 0.876 | 0.604 |
batch 2 | 0.842 | 0.717 | 0.866 | 0.654 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
TF family | Jun-related {1.1.1} (TFClass) |
TF subfamily | ATF2 {1.1.1.3} (TFClass) |
TFClass ID | TFClass: 1.1.1.3.1 |
HGNC | HGNC:784 |
MGI | MGI:109349 |
EntrezGene (human) | GeneID:1386 (SSTAR profile) |
EntrezGene (mouse) | GeneID:11909 (SSTAR profile) |
UniProt ID (human) | ATF2_HUMAN |
UniProt ID (mouse) | ATF2_MOUSE |
UniProt AC (human) | P15336 (TFClass) |
UniProt AC (mouse) | P16951 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 5 human, 2 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 2 |
PCM | ATF2.H12INVIVO.0.PSM.A.pcm |
PWM | ATF2.H12INVIVO.0.PSM.A.pwm |
PFM | ATF2.H12INVIVO.0.PSM.A.pfm |
Alignment | ATF2.H12INVIVO.0.PSM.A.words.tsv |
Threshold to P-value map | ATF2.H12INVIVO.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | ATF2.H12INVIVO.0.PSM.A_jaspar_format.txt |
MEME format | ATF2.H12INVIVO.0.PSM.A_meme_format.meme |
Transfac format | ATF2.H12INVIVO.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 288.0 | 85.0 | 523.0 | 85.0 |
02 | 638.0 | 9.0 | 329.0 | 5.0 |
03 | 3.0 | 1.0 | 2.0 | 975.0 |
04 | 1.0 | 1.0 | 970.0 | 9.0 |
05 | 972.0 | 1.0 | 1.0 | 7.0 |
06 | 1.0 | 643.0 | 35.0 | 302.0 |
07 | 1.0 | 3.0 | 976.0 | 1.0 |
08 | 6.0 | 12.0 | 2.0 | 961.0 |
09 | 198.0 | 772.0 | 7.0 | 4.0 |
10 | 949.0 | 3.0 | 16.0 | 13.0 |
11 | 29.0 | 264.0 | 168.0 | 520.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.294 | 0.087 | 0.533 | 0.087 |
02 | 0.65 | 0.009 | 0.335 | 0.005 |
03 | 0.003 | 0.001 | 0.002 | 0.994 |
04 | 0.001 | 0.001 | 0.989 | 0.009 |
05 | 0.991 | 0.001 | 0.001 | 0.007 |
06 | 0.001 | 0.655 | 0.036 | 0.308 |
07 | 0.001 | 0.003 | 0.995 | 0.001 |
08 | 0.006 | 0.012 | 0.002 | 0.98 |
09 | 0.202 | 0.787 | 0.007 | 0.004 |
10 | 0.967 | 0.003 | 0.016 | 0.013 |
11 | 0.03 | 0.269 | 0.171 | 0.53 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.16 | -1.047 | 0.754 | -1.047 |
02 | 0.952 | -3.137 | 0.292 | -3.604 |
03 | -3.957 | -4.508 | -4.195 | 1.375 |
04 | -4.508 | -4.508 | 1.37 | -3.137 |
05 | 1.372 | -4.508 | -4.508 | -3.343 |
06 | -4.508 | 0.96 | -1.906 | 0.207 |
07 | -4.508 | -3.957 | 1.376 | -4.508 |
08 | -3.465 | -2.89 | -4.195 | 1.36 |
09 | -0.212 | 1.142 | -3.343 | -3.765 |
10 | 1.348 | -3.957 | -2.634 | -2.82 |
11 | -2.084 | 0.073 | -0.375 | 0.748 |
P-value | Threshold |
---|---|
0.001 | 1.925425 |
0.0005 | 3.445525 |
0.0001 | 6.212805 |