MotifATF2.H12INVIVO.0.PSM.A
Gene (human)ATF2
(GeneCards)
Gene synonyms (human)CREB2, CREBP1
Gene (mouse)Atf2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusnRTGAYGTCAY
GC content44.69%
Information content (bits; total / per base)15.126 / 1.375
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words981

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.984 0.996 0.946 0.984 0.992 0.999 6.699 7.875 811.237 1230.921
Mouse 2 (12) 0.84 0.905 0.772 0.863 0.816 0.884 3.437 4.197 228.974 288.553

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.978 0.965 0.942 0.922 0.848 0.834
best 0.997 0.995 0.989 0.985 0.929 0.924
Methyl HT-SELEX, 2 experiments median 0.991 0.985 0.971 0.961 0.894 0.886
best 0.997 0.995 0.989 0.985 0.929 0.924
Non-Methyl HT-SELEX, 2 experiments median 0.959 0.936 0.916 0.886 0.824 0.803
best 0.971 0.954 0.93 0.906 0.836 0.819

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 28.563 57.113 0.341 0.343

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.836 0.58 0.876 0.604
batch 2 0.842 0.717 0.866 0.654
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyJun-related {1.1.1} (TFClass)
TF subfamilyATF2 {1.1.1.3} (TFClass)
TFClass IDTFClass: 1.1.1.3.1
HGNCHGNC:784
MGIMGI:109349
EntrezGene (human)GeneID:1386
(SSTAR profile)
EntrezGene (mouse)GeneID:11909
(SSTAR profile)
UniProt ID (human)ATF2_HUMAN
UniProt ID (mouse)ATF2_MOUSE
UniProt AC (human)P15336
(TFClass)
UniProt AC (mouse)P16951
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01288.085.0523.085.0
02638.09.0329.05.0
033.01.02.0975.0
041.01.0970.09.0
05972.01.01.07.0
061.0643.035.0302.0
071.03.0976.01.0
086.012.02.0961.0
09198.0772.07.04.0
10949.03.016.013.0
1129.0264.0168.0520.0
PFM
ACGT
010.2940.0870.5330.087
020.650.0090.3350.005
030.0030.0010.0020.994
040.0010.0010.9890.009
050.9910.0010.0010.007
060.0010.6550.0360.308
070.0010.0030.9950.001
080.0060.0120.0020.98
090.2020.7870.0070.004
100.9670.0030.0160.013
110.030.2690.1710.53
PWM
ACGT
010.16-1.0470.754-1.047
020.952-3.1370.292-3.604
03-3.957-4.508-4.1951.375
04-4.508-4.5081.37-3.137
051.372-4.508-4.508-3.343
06-4.5080.96-1.9060.207
07-4.508-3.9571.376-4.508
08-3.465-2.89-4.1951.36
09-0.2121.142-3.343-3.765
101.348-3.957-2.634-2.82
11-2.0840.073-0.3750.748
Standard thresholds
P-value Threshold
0.001 1.925425
0.0005 3.445525
0.0001 6.212805