ATF2.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF2.H12CORE.1.P.B
Gene (human)	ATF2 (GeneCards)
Gene synonyms (human)	CREB2, CREBP1
Gene (mouse)	Atf2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	dATGAYGTCAT
GC content	36.42%
Information content (bits; total / per base)	15.549 / 1.414
Data sources	ChIP-Seq
Aligned words	986

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (35)	0.978	0.994	0.923	0.976	0.989	0.998	6.016	7.095	801.086	1199.377
Mouse	2 (12)	0.818	0.883	0.741	0.826	0.803	0.865	3.225	3.701	206.893	263.125

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.971	0.955	0.929	0.907	0.835	0.819
Overall, 4 experiments	best	0.997	0.995	0.989	0.985	0.93	0.924
Methyl HT-SELEX, 2 experiments	median	0.99	0.984	0.969	0.959	0.893	0.884
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.989	0.985	0.93	0.924
Non-Methyl HT-SELEX, 2 experiments	median	0.945	0.916	0.893	0.858	0.802	0.777
Non-Methyl HT-SELEX, 2 experiments	best	0.959	0.937	0.909	0.88	0.814	0.793

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.998	11.581	0.21	0.239

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.746	0.399	0.683	0.444
batch 2	0.806	0.636	0.747	0.527

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	ATF2 {1.1.1.3} (TFClass)
TFClass ID	TFClass: 1.1.1.3.1
HGNC	HGNC:784
MGI	MGI:109349
EntrezGene (human)	GeneID:1386 (SSTAR profile)
EntrezGene (mouse)	GeneID:11909 (SSTAR profile)
UniProt ID (human)	ATF2_HUMAN
UniProt ID (mouse)	ATF2_MOUSE
UniProt AC (human)	P15336 (TFClass)
UniProt AC (mouse)	P16951 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	ATF2.H12CORE.1.P.B.pcm
PWM	ATF2.H12CORE.1.P.B.pwm
PFM	ATF2.H12CORE.1.P.B.pfm
Alignment	ATF2.H12CORE.1.P.B.words.tsv
Threshold to P-value map	ATF2.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	ATF2.H12CORE.1.P.B_jaspar_format.txt
MEME format	ATF2.H12CORE.1.P.B_meme_format.meme
Transfac format	ATF2.H12CORE.1.P.B_transfac_format.txt
Homer format	ATF2.H12CORE.1.P.B_homer_format_0.001.txt ATF2.H12CORE.1.P.B_homer_format_0.0005.txt ATF2.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	348.0	101.0	386.0	151.0
02	788.0	6.0	184.0	8.0
03	8.0	7.0	2.0	969.0
04	9.0	2.0	955.0	20.0
05	975.0	3.0	6.0	2.0
06	6.0	253.0	49.0	678.0
07	8.0	1.0	969.0	8.0
08	14.0	8.0	1.0	963.0
09	160.0	813.0	10.0	3.0
10	967.0	3.0	10.0	6.0
11	13.0	121.0	60.0	792.0

PFM

	A	C	G	T
01	0.353	0.102	0.391	0.153
02	0.799	0.006	0.187	0.008
03	0.008	0.007	0.002	0.983
04	0.009	0.002	0.969	0.02
05	0.989	0.003	0.006	0.002
06	0.006	0.257	0.05	0.688
07	0.008	0.001	0.983	0.008
08	0.014	0.008	0.001	0.977
09	0.162	0.825	0.01	0.003
10	0.981	0.003	0.01	0.006
11	0.013	0.123	0.061	0.803

PWM

	A	C	G	T
01	0.343	-0.882	0.446	-0.486
02	1.157	-3.47	-0.29	-3.24
03	-3.24	-3.348	-4.2	1.364
04	-3.142	-4.2	1.349	-2.436
05	1.37	-3.962	-3.47	-4.2
06	-3.47	0.026	-1.588	1.007
07	-3.24	-4.512	1.364	-3.24
08	-2.759	-3.24	-4.512	1.358
09	-0.428	1.189	-3.053	-3.962
10	1.362	-3.962	-3.053	-3.47
11	-2.825	-0.704	-1.392	1.162

Standard thresholds

P-value	Threshold
0.001	2.12827
0.0005	3.419505
0.0001	6.245025