MotifARX.H12CORE.1.SM.B
Gene (human)ARX
(GeneCards)
Gene synonyms (human)
Gene (mouse)Arx
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnnYRATTARbbn
GC content35.72%
Information content (bits; total / per base)10.658 / 0.888
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8668

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.981 0.967 0.974 0.956 0.956 0.934
best 0.988 0.981 0.985 0.974 0.975 0.962
Methyl HT-SELEX, 1 experiments median 0.962 0.936 0.948 0.917 0.925 0.889
best 0.962 0.936 0.948 0.917 0.925 0.889
Non-Methyl HT-SELEX, 5 experiments median 0.985 0.975 0.978 0.964 0.956 0.937
best 0.988 0.981 0.985 0.974 0.975 0.962

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.75 0.516 0.74 0.521
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyARX {3.1.3.3} (TFClass)
TFClass IDTFClass: 3.1.3.3.1
HGNCHGNC:18060
MGIMGI:1097716
EntrezGene (human)GeneID:170302
(SSTAR profile)
EntrezGene (mouse)GeneID:11878
(SSTAR profile)
UniProt ID (human)ARX_HUMAN
UniProt ID (mouse)ARX_MOUSE
UniProt AC (human)Q96QS3
(TFClass)
UniProt AC (mouse)O35085
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
012122.252363.252172.252010.25
021024.02697.02570.02377.0
03410.03008.0548.04702.0
046430.0480.01727.031.0
058668.00.00.00.0
060.00.00.08668.0
070.00.00.08668.0
088668.00.00.00.0
092234.0681.05725.028.0
10628.03266.02602.02172.0
11987.251884.253357.252439.25
122013.02132.01939.02584.0
PFM
ACGT
010.2450.2730.2510.232
020.1180.3110.2960.274
030.0470.3470.0630.542
040.7420.0550.1990.004
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
081.00.00.00.0
090.2580.0790.660.003
100.0720.3770.30.251
110.1140.2170.3870.281
120.2320.2460.2240.298
PWM
ACGT
01-0.0210.0870.002-0.075
02-0.7480.2190.170.092
03-1.660.328-1.3720.774
041.087-1.504-0.227-4.178
051.386-6.864-6.864-6.864
06-6.864-6.864-6.8641.386
07-6.864-6.864-6.8641.386
081.386-6.864-6.864-6.864
090.03-1.1550.971-4.272
10-1.2360.410.1830.002
11-0.785-0.140.4370.118
12-0.074-0.016-0.1110.176
Standard thresholds
P-value Threshold
0.001 4.709215
0.0005 5.978815
0.0001 7.743005