Motif | ARX.H12CORE.0.S.B |
Gene (human) | ARX (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Arx |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | ARX.H12CORE.0.S.B |
Gene (human) | ARX (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Arx |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 18 |
Consensus | dhTAATYWAATTARbnnn |
GC content | 24.25% |
Information content (bits; total / per base) | 17.717 / 0.984 |
Data sources | HT-SELEX |
Aligned words | 6919 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.999 | 0.997 | 0.995 | 0.993 | 0.977 | 0.968 |
best | 0.999 | 0.998 | 0.998 | 0.997 | 0.992 | 0.99 | |
Methyl HT-SELEX, 1 experiments | median | 0.969 | 0.948 | 0.951 | 0.924 | 0.923 | 0.891 |
best | 0.969 | 0.948 | 0.951 | 0.924 | 0.923 | 0.891 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.999 | 0.997 | 0.998 | 0.997 | 0.988 | 0.986 |
best | 0.999 | 0.998 | 0.998 | 0.997 | 0.992 | 0.99 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.769 | 0.52 | 0.781 | 0.573 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | ARX {3.1.3.3} (TFClass) |
TFClass ID | TFClass: 3.1.3.3.1 |
HGNC | HGNC:18060 |
MGI | MGI:1097716 |
EntrezGene (human) | GeneID:170302 (SSTAR profile) |
EntrezGene (mouse) | GeneID:11878 (SSTAR profile) |
UniProt ID (human) | ARX_HUMAN |
UniProt ID (mouse) | ARX_MOUSE |
UniProt AC (human) | Q96QS3 (TFClass) |
UniProt AC (mouse) | O35085 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 1 |
PCM | ARX.H12CORE.0.S.B.pcm |
PWM | ARX.H12CORE.0.S.B.pwm |
PFM | ARX.H12CORE.0.S.B.pfm |
Alignment | ARX.H12CORE.0.S.B.words.tsv |
Threshold to P-value map | ARX.H12CORE.0.S.B.thr |
Motif in other formats | |
JASPAR format | ARX.H12CORE.0.S.B_jaspar_format.txt |
MEME format | ARX.H12CORE.0.S.B_meme_format.meme |
Transfac format | ARX.H12CORE.0.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2974.0 | 1128.0 | 1373.0 | 1444.0 |
02 | 1015.75 | 1833.75 | 986.75 | 3082.75 |
03 | 274.0 | 92.0 | 61.0 | 6492.0 |
04 | 6435.0 | 61.0 | 338.0 | 85.0 |
05 | 6484.0 | 111.0 | 300.0 | 24.0 |
06 | 232.0 | 422.0 | 255.0 | 6010.0 |
07 | 5.0 | 3481.0 | 188.0 | 3245.0 |
08 | 1133.0 | 1033.0 | 377.0 | 4376.0 |
09 | 5788.0 | 5.0 | 1126.0 | 0.0 |
10 | 6914.0 | 0.0 | 5.0 | 0.0 |
11 | 0.0 | 0.0 | 0.0 | 6919.0 |
12 | 0.0 | 19.0 | 0.0 | 6900.0 |
13 | 6805.0 | 2.0 | 105.0 | 7.0 |
14 | 2507.0 | 607.0 | 3733.0 | 72.0 |
15 | 624.0 | 2340.0 | 1165.0 | 2790.0 |
16 | 1252.0 | 1587.0 | 1702.0 | 2378.0 |
17 | 2574.5 | 1520.5 | 1318.5 | 1505.5 |
18 | 2242.75 | 1482.75 | 1443.75 | 1749.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.43 | 0.163 | 0.198 | 0.209 |
02 | 0.147 | 0.265 | 0.143 | 0.446 |
03 | 0.04 | 0.013 | 0.009 | 0.938 |
04 | 0.93 | 0.009 | 0.049 | 0.012 |
05 | 0.937 | 0.016 | 0.043 | 0.003 |
06 | 0.034 | 0.061 | 0.037 | 0.869 |
07 | 0.001 | 0.503 | 0.027 | 0.469 |
08 | 0.164 | 0.149 | 0.054 | 0.632 |
09 | 0.837 | 0.001 | 0.163 | 0.0 |
10 | 0.999 | 0.0 | 0.001 | 0.0 |
11 | 0.0 | 0.0 | 0.0 | 1.0 |
12 | 0.0 | 0.003 | 0.0 | 0.997 |
13 | 0.984 | 0.0 | 0.015 | 0.001 |
14 | 0.362 | 0.088 | 0.54 | 0.01 |
15 | 0.09 | 0.338 | 0.168 | 0.403 |
16 | 0.181 | 0.229 | 0.246 | 0.344 |
17 | 0.372 | 0.22 | 0.191 | 0.218 |
18 | 0.324 | 0.214 | 0.209 | 0.253 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.541 | -0.427 | -0.231 | -0.18 |
02 | -0.531 | 0.058 | -0.56 | 0.577 |
03 | -1.836 | -2.911 | -3.311 | 1.322 |
04 | 1.313 | -3.311 | -1.627 | -2.989 |
05 | 1.32 | -2.728 | -1.746 | -4.191 |
06 | -2.001 | -1.407 | -1.907 | 1.245 |
07 | -5.481 | 0.699 | -2.209 | 0.629 |
08 | -0.422 | -0.515 | -1.519 | 0.927 |
09 | 1.207 | -5.481 | -0.429 | -6.664 |
10 | 1.385 | -6.664 | -5.481 | -6.664 |
11 | -6.664 | -6.664 | -6.664 | 1.385 |
12 | -6.664 | -4.403 | -6.664 | 1.383 |
13 | 1.369 | -6.019 | -2.782 | -5.237 |
14 | 0.371 | -1.045 | 0.769 | -3.15 |
15 | -1.017 | 0.302 | -0.395 | 0.478 |
16 | -0.323 | -0.086 | -0.016 | 0.318 |
17 | 0.397 | -0.129 | -0.271 | -0.139 |
18 | 0.259 | -0.154 | -0.18 | 0.011 |
P-value | Threshold |
---|---|
0.001 | -0.18749 |
0.0005 | 1.51596 |
0.0001 | 5.02026 |