AP2E.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	AP2E.H12INVITRO.0.SM.B
Gene (human)	TFAP2E (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tfap2e
Gene synonyms (mouse)	Tcfap2e
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	ndbGCCTSAGGSbRhn
GC content	61.62%
Information content (bits; total / per base)	14.474 / 0.905
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9965

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.997	0.997	0.995	0.994	0.991
Overall, 2 experiments	best	0.999	0.999	0.999	0.998	0.997	0.996
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.999	0.998	0.997	0.996
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.999	0.998	0.997	0.996
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.995	0.993	0.991	0.986
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.995	0.993	0.991	0.986

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-span-helix factors (bHSH) {1.3} (TFClass)
TF family	AP-2 {1.3.1} (TFClass)
TF subfamily	{1.3.1.0} (TFClass)
TFClass ID	TFClass: 1.3.1.0.5
HGNC	HGNC:30774
MGI	MGI:2679630
EntrezGene (human)	GeneID:339488 (SSTAR profile)
EntrezGene (mouse)	GeneID:332937 (SSTAR profile)
UniProt ID (human)	AP2E_HUMAN
UniProt ID (mouse)	AP2E_MOUSE
UniProt AC (human)	Q6VUC0 (TFClass)
UniProt AC (mouse)	Q6VUP9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	AP2E.H12INVITRO.0.SM.B.pcm
PWM	AP2E.H12INVITRO.0.SM.B.pwm
PFM	AP2E.H12INVITRO.0.SM.B.pfm
Alignment	AP2E.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	AP2E.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	AP2E.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	AP2E.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	AP2E.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	AP2E.H12INVITRO.0.SM.B_homer_format_0.001.txt AP2E.H12INVITRO.0.SM.B_homer_format_0.0005.txt AP2E.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3023.75	2071.75	2288.75	2580.75
02	2755.0	1056.0	1896.0	4258.0
03	1501.0	1915.0	1517.0	5032.0
04	188.0	1598.0	8035.0	144.0
05	3.0	9957.0	4.0	1.0
06	1.0	9867.0	9.0	88.0
07	9.0	985.0	6.0	8965.0
08	536.0	4414.0	4320.0	695.0
09	8526.0	35.0	1401.0	3.0
10	663.0	3.0	9296.0	3.0
11	6.0	3.0	9951.0	5.0
12	170.0	3261.0	6467.0	67.0
13	1205.0	5866.0	1292.0	1602.0
14	5722.0	589.0	2797.0	857.0
15	2505.25	2092.25	734.25	4633.25
16	3134.5	1520.5	3006.5	2303.5

PFM

	A	C	G	T
01	0.303	0.208	0.23	0.259
02	0.276	0.106	0.19	0.427
03	0.151	0.192	0.152	0.505
04	0.019	0.16	0.806	0.014
05	0.0	0.999	0.0	0.0
06	0.0	0.99	0.001	0.009
07	0.001	0.099	0.001	0.9
08	0.054	0.443	0.434	0.07
09	0.856	0.004	0.141	0.0
10	0.067	0.0	0.933	0.0
11	0.001	0.0	0.999	0.001
12	0.017	0.327	0.649	0.007
13	0.121	0.589	0.13	0.161
14	0.574	0.059	0.281	0.086
15	0.251	0.21	0.074	0.465
16	0.315	0.153	0.302	0.231

PWM

	A	C	G	T
01	0.194	-0.184	-0.085	0.035
02	0.101	-0.857	-0.273	0.536
03	-0.506	-0.263	-0.495	0.703
04	-2.573	-0.444	1.17	-2.836
05	-6.153	1.385	-5.981	-6.627
06	-6.627	1.376	-5.397	-3.318
07	-5.397	-0.926	-5.705	1.28
08	-1.533	0.572	0.55	-1.274
09	1.23	-4.202	-0.575	-6.153
10	-1.321	-6.153	1.316	-6.153
11	-5.705	-6.153	1.384	-5.833
12	-2.672	0.269	0.953	-3.583
13	-0.725	0.856	-0.656	-0.441
14	0.831	-1.439	0.116	-1.065
15	0.006	-0.174	-1.219	0.62
16	0.229	-0.493	0.188	-0.078

Standard thresholds

P-value	Threshold
0.001	2.10266
0.0005	3.64306
0.0001	6.72261