MotifAP2E.H12CORE.0.SM.B
Gene (human)TFAP2E
(GeneCards)
Gene synonyms (human)
Gene (mouse)Tfap2e
Gene synonyms (mouse)Tcfap2e
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusndbGCCTSAGGSbRhn
GC content61.62%
Information content (bits; total / per base)14.474 / 0.905
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9965

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.997 0.995 0.994 0.991
best 0.999 0.999 0.999 0.998 0.997 0.996
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.997 0.996
best 0.999 0.999 0.999 0.998 0.997 0.996
Non-Methyl HT-SELEX, 1 experiments median 0.997 0.995 0.995 0.993 0.991 0.986
best 0.997 0.995 0.995 0.993 0.991 0.986
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-span-helix factors (bHSH) {1.3} (TFClass)
TF familyAP-2 {1.3.1} (TFClass)
TF subfamily {1.3.1.0} (TFClass)
TFClass IDTFClass: 1.3.1.0.5
HGNCHGNC:30774
MGIMGI:2679630
EntrezGene (human)GeneID:339488
(SSTAR profile)
EntrezGene (mouse)GeneID:332937
(SSTAR profile)
UniProt ID (human)AP2E_HUMAN
UniProt ID (mouse)AP2E_MOUSE
UniProt AC (human)Q6VUC0
(TFClass)
UniProt AC (mouse)Q6VUP9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013023.752071.752288.752580.75
022755.01056.01896.04258.0
031501.01915.01517.05032.0
04188.01598.08035.0144.0
053.09957.04.01.0
061.09867.09.088.0
079.0985.06.08965.0
08536.04414.04320.0695.0
098526.035.01401.03.0
10663.03.09296.03.0
116.03.09951.05.0
12170.03261.06467.067.0
131205.05866.01292.01602.0
145722.0589.02797.0857.0
152505.252092.25734.254633.25
163134.51520.53006.52303.5
PFM
ACGT
010.3030.2080.230.259
020.2760.1060.190.427
030.1510.1920.1520.505
040.0190.160.8060.014
050.00.9990.00.0
060.00.990.0010.009
070.0010.0990.0010.9
080.0540.4430.4340.07
090.8560.0040.1410.0
100.0670.00.9330.0
110.0010.00.9990.001
120.0170.3270.6490.007
130.1210.5890.130.161
140.5740.0590.2810.086
150.2510.210.0740.465
160.3150.1530.3020.231
PWM
ACGT
010.194-0.184-0.0850.035
020.101-0.857-0.2730.536
03-0.506-0.263-0.4950.703
04-2.573-0.4441.17-2.836
05-6.1531.385-5.981-6.627
06-6.6271.376-5.397-3.318
07-5.397-0.926-5.7051.28
08-1.5330.5720.55-1.274
091.23-4.202-0.575-6.153
10-1.321-6.1531.316-6.153
11-5.705-6.1531.384-5.833
12-2.6720.2690.953-3.583
13-0.7250.856-0.656-0.441
140.831-1.4390.116-1.065
150.006-0.174-1.2190.62
160.229-0.4930.188-0.078
Standard thresholds
P-value Threshold
0.001 2.10266
0.0005 3.64306
0.0001 6.72261