Motif | AP2B.H12CORE.0.SM.B |
Gene (human) | TFAP2B (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Tfap2b |
Gene synonyms (mouse) | Tcfap2b |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | AP2B.H12CORE.0.SM.B |
Gene (human) | TFAP2B (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Tfap2b |
Gene synonyms (mouse) | Tcfap2b |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 18 |
Consensus | ddnSCCYvRGGSndhdhn |
GC content | 57.72% |
Information content (bits; total / per base) | 10.857 / 0.603 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9846 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 3 experiments | median | 0.977 | 0.959 | 0.949 | 0.915 | 0.928 | 0.891 |
best | 0.993 | 0.989 | 0.965 | 0.944 | 0.935 | 0.91 | |
Methyl HT-SELEX, 1 experiments | median | 0.977 | 0.959 | 0.965 | 0.944 | 0.935 | 0.91 |
best | 0.977 | 0.959 | 0.965 | 0.944 | 0.935 | 0.91 | |
Non-Methyl HT-SELEX, 2 experiments | median | 0.976 | 0.959 | 0.893 | 0.886 | 0.786 | 0.797 |
best | 0.993 | 0.989 | 0.949 | 0.915 | 0.928 | 0.891 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic helix-span-helix factors (bHSH) {1.3} (TFClass) |
TF family | AP-2 {1.3.1} (TFClass) |
TF subfamily | {1.3.1.0} (TFClass) |
TFClass ID | TFClass: 1.3.1.0.2 |
HGNC | HGNC:11743 |
MGI | MGI:104672 |
EntrezGene (human) | GeneID:7021 (SSTAR profile) |
EntrezGene (mouse) | GeneID:21419 (SSTAR profile) |
UniProt ID (human) | AP2B_HUMAN |
UniProt ID (mouse) | AP2B_MOUSE |
UniProt AC (human) | Q92481 (TFClass) |
UniProt AC (mouse) | Q61313 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 1 |
PCM | AP2B.H12CORE.0.SM.B.pcm |
PWM | AP2B.H12CORE.0.SM.B.pwm |
PFM | AP2B.H12CORE.0.SM.B.pfm |
Alignment | AP2B.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | AP2B.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | AP2B.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | AP2B.H12CORE.0.SM.B_meme_format.meme |
Transfac format | AP2B.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 5421.0 | 1171.0 | 1550.0 | 1704.0 |
02 | 3467.25 | 1288.25 | 1557.25 | 3533.25 |
03 | 2868.0 | 2462.0 | 1759.0 | 2757.0 |
04 | 355.0 | 2566.0 | 6589.0 | 336.0 |
05 | 156.0 | 9301.0 | 196.0 | 193.0 |
06 | 145.0 | 8812.0 | 193.0 | 696.0 |
07 | 163.0 | 2473.0 | 1099.0 | 6111.0 |
08 | 1049.0 | 3719.0 | 4133.0 | 945.0 |
09 | 5720.0 | 767.0 | 3308.0 | 51.0 |
10 | 629.0 | 19.0 | 9175.0 | 23.0 |
11 | 79.0 | 49.0 | 9661.0 | 57.0 |
12 | 253.0 | 4592.0 | 4627.0 | 374.0 |
13 | 2008.0 | 3206.0 | 2688.0 | 1944.0 |
14 | 5554.0 | 901.0 | 1693.0 | 1698.0 |
15 | 2556.0 | 1464.0 | 1065.0 | 4761.0 |
16 | 2846.0 | 1085.0 | 1774.0 | 4141.0 |
17 | 2173.25 | 1761.25 | 1448.25 | 4463.25 |
18 | 2534.0 | 1996.0 | 2143.0 | 3173.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.551 | 0.119 | 0.157 | 0.173 |
02 | 0.352 | 0.131 | 0.158 | 0.359 |
03 | 0.291 | 0.25 | 0.179 | 0.28 |
04 | 0.036 | 0.261 | 0.669 | 0.034 |
05 | 0.016 | 0.945 | 0.02 | 0.02 |
06 | 0.015 | 0.895 | 0.02 | 0.071 |
07 | 0.017 | 0.251 | 0.112 | 0.621 |
08 | 0.107 | 0.378 | 0.42 | 0.096 |
09 | 0.581 | 0.078 | 0.336 | 0.005 |
10 | 0.064 | 0.002 | 0.932 | 0.002 |
11 | 0.008 | 0.005 | 0.981 | 0.006 |
12 | 0.026 | 0.466 | 0.47 | 0.038 |
13 | 0.204 | 0.326 | 0.273 | 0.197 |
14 | 0.564 | 0.092 | 0.172 | 0.172 |
15 | 0.26 | 0.149 | 0.108 | 0.484 |
16 | 0.289 | 0.11 | 0.18 | 0.421 |
17 | 0.221 | 0.179 | 0.147 | 0.453 |
18 | 0.257 | 0.203 | 0.218 | 0.322 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.789 | -0.742 | -0.462 | -0.367 |
02 | 0.342 | -0.647 | -0.457 | 0.361 |
03 | 0.153 | 0.0 | -0.336 | 0.113 |
04 | -1.931 | 0.042 | 0.984 | -1.986 |
05 | -2.745 | 1.329 | -2.52 | -2.535 |
06 | -2.817 | 1.275 | -2.535 | -1.261 |
07 | -2.702 | 0.005 | -0.805 | 0.909 |
08 | -0.852 | 0.412 | 0.518 | -0.956 |
09 | 0.843 | -1.164 | 0.295 | -3.834 |
10 | -1.362 | -4.751 | 1.315 | -4.579 |
11 | -3.411 | -3.872 | 1.367 | -3.727 |
12 | -2.267 | 0.623 | 0.631 | -1.879 |
13 | -0.203 | 0.264 | 0.088 | -0.236 |
14 | 0.813 | -1.003 | -0.374 | -0.371 |
15 | 0.038 | -0.519 | -0.837 | 0.659 |
16 | 0.145 | -0.818 | -0.327 | 0.52 |
17 | -0.124 | -0.334 | -0.53 | 0.595 |
18 | 0.029 | -0.209 | -0.138 | 0.254 |
P-value | Threshold |
---|---|
0.001 | 4.49076 |
0.0005 | 5.42611 |
0.0001 | 7.31656 |