ANDR.H12RSNP.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12RSNP.2.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	19
Consensus	WKYhMYbbnnWRTKKdYhb
GC content	41.91%
Information content (bits; total / per base)	8.445 / 0.444
Data sources	ChIP-Seq
Aligned words	976

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.725	0.851	0.624	0.814	0.786	0.892	3.084	4.984	64.921	380.222
Mouse	20 (35)	0.557	0.764	0.416	0.754	0.663	0.821	1.986	4.738	19.357	107.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.536	0.521	0.529	0.517	0.519	0.513
Non-Methyl HT-SELEX, 3 experiments	best	0.579	0.554	0.554	0.538	0.536	0.527

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.57	13.767	0.05	0.022

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12RSNP.2.P.B.pcm
PWM	ANDR.H12RSNP.2.P.B.pwm
PFM	ANDR.H12RSNP.2.P.B.pfm
Alignment	ANDR.H12RSNP.2.P.B.words.tsv
Threshold to P-value map	ANDR.H12RSNP.2.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12RSNP.2.P.B_jaspar_format.txt
MEME format	ANDR.H12RSNP.2.P.B_meme_format.meme
Transfac format	ANDR.H12RSNP.2.P.B_transfac_format.txt
Homer format	ANDR.H12RSNP.2.P.B_homer_format_0.001.txt ANDR.H12RSNP.2.P.B_homer_format_0.0005.txt ANDR.H12RSNP.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	165.0	72.0	114.0	625.0
02	60.0	112.0	639.0	165.0
03	89.0	125.0	81.0	681.0
04	170.0	211.0	162.0	433.0
05	123.0	671.0	69.0	113.0
06	132.0	365.0	16.0	463.0
07	137.0	147.0	196.0	496.0
08	129.0	188.0	262.0	397.0
09	211.0	231.0	256.0	278.0
10	208.0	344.0	180.0	244.0
11	158.0	33.0	55.0	730.0
12	206.0	106.0	613.0	51.0
13	47.0	64.0	67.0	798.0
14	47.0	96.0	211.0	622.0
15	40.0	60.0	145.0	731.0
16	340.0	68.0	484.0	84.0
17	74.0	548.0	63.0	291.0
18	266.0	204.0	57.0	449.0
19	122.0	271.0	186.0	397.0

PFM

	A	C	G	T
01	0.169	0.074	0.117	0.64
02	0.061	0.115	0.655	0.169
03	0.091	0.128	0.083	0.698
04	0.174	0.216	0.166	0.444
05	0.126	0.688	0.071	0.116
06	0.135	0.374	0.016	0.474
07	0.14	0.151	0.201	0.508
08	0.132	0.193	0.268	0.407
09	0.216	0.237	0.262	0.285
10	0.213	0.352	0.184	0.25
11	0.162	0.034	0.056	0.748
12	0.211	0.109	0.628	0.052
13	0.048	0.066	0.069	0.818
14	0.048	0.098	0.216	0.637
15	0.041	0.061	0.149	0.749
16	0.348	0.07	0.496	0.086
17	0.076	0.561	0.065	0.298
18	0.273	0.209	0.058	0.46
19	0.125	0.278	0.191	0.407

PWM

	A	C	G	T
01	-0.388	-1.204	-0.753	0.936
02	-1.382	-0.77	0.958	-0.388
03	-0.996	-0.662	-1.089	1.022
04	-0.358	-0.144	-0.406	0.571
05	-0.678	1.007	-1.245	-0.762
06	-0.608	0.4	-2.629	0.637
07	-0.572	-0.502	-0.217	0.706
08	-0.631	-0.259	0.071	0.484
09	-0.144	-0.054	0.048	0.13
10	-0.158	0.341	-0.302	0.0
11	-0.431	-1.957	-1.466	1.091
12	-0.168	-0.825	0.917	-1.539
13	-1.618	-1.319	-1.274	1.18
14	-1.618	-0.922	-0.144	0.932
15	-1.773	-1.382	-0.516	1.093
16	0.33	-1.26	0.681	-1.053
17	-1.177	0.805	-1.334	0.175
18	0.086	-0.178	-1.431	0.607
19	-0.686	0.104	-0.269	0.484

Standard thresholds

P-value	Threshold
0.001	4.82306
0.0005	5.51866
0.0001	6.98876