MotifANDR.H12RSNP.1.S.C
Gene (human)AR
(GeneCards)
Gene synonyms (human)DHTR, NR3C4
Gene (mouse)Ar
Gene synonyms (mouse)Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length8
ConsensusdTGTTCbn
GC content46.34%
Information content (bits; total / per base)8.446 / 1.056
Data sourcesHT-SELEX
Aligned words6603

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 237 (413) 0.761 0.88 0.604 0.781 0.693 0.795 1.648 2.195 83.284 201.658
Mouse 20 (35) 0.756 0.838 0.631 0.731 0.728 0.788 1.864 2.088 133.201 186.143

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 3 experiments median 0.681 0.652 0.596 0.589 0.553 0.555
best 0.949 0.916 0.919 0.88 0.828 0.805

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.117 1.223 0.021 0.006
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyGR-like (NR3C) {2.1.1.1} (TFClass)
TFClass IDTFClass: 2.1.1.1.4
HGNCHGNC:644
MGIMGI:88064
EntrezGene (human)GeneID:367
(SSTAR profile)
EntrezGene (mouse)GeneID:11835
(SSTAR profile)
UniProt ID (human)ANDR_HUMAN
UniProt ID (mouse)ANDR_MOUSE
UniProt AC (human)P10275
(TFClass)
UniProt AC (mouse)P19091
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 237 human, 20 mouse
HT-SELEX 3
Methyl-HT-SELEX 0
PCM
ACGT
012161.751006.752329.751104.75
02105.75787.7593.755615.75
03240.012.06320.031.0
040.00.00.06603.0
052083.00.00.04520.0
060.06603.00.00.0
07844.03187.01049.01523.0
081195.252049.251042.252316.25
PFM
ACGT
010.3270.1520.3530.167
020.0160.1190.0140.85
030.0360.0020.9570.005
040.00.00.01.0
050.3150.00.00.685
060.01.00.00.0
070.1280.4830.1590.231
080.1810.310.1580.351
PWM
ACGT
010.269-0.4940.344-0.401
02-2.729-0.738-2.8471.223
03-1.921-4.7571.342-3.908
04-6.622-6.622-6.6221.385
050.232-6.622-6.6221.006
06-6.6221.385-6.622-6.622
07-0.670.657-0.453-0.08
08-0.3220.216-0.4590.338
Standard thresholds
P-value Threshold
0.001 5.617575
0.0005 6.17939
0.0001 6.94118