ANDR.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12RSNP.0.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	RGdACAbKbTGTWCYhbnh
GC content	46.75%
Information content (bits; total / per base)	15.695 / 0.826
Data sources	ChIP-Seq
Aligned words	237

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.852	0.983	0.782	0.975	0.818	0.978	3.153	6.774	194.824	538.678
Mouse	20 (35)	0.916	0.98	0.875	0.961	0.919	0.982	4.496	6.197	393.602	599.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.68	0.702	0.577	0.601	0.535	0.556
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.993	0.991	0.91	0.912

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.308	5.328	0.033	0.011

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12RSNP.0.P.B.pcm
PWM	ANDR.H12RSNP.0.P.B.pwm
PFM	ANDR.H12RSNP.0.P.B.pfm
Alignment	ANDR.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	ANDR.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12RSNP.0.P.B_jaspar_format.txt
MEME format	ANDR.H12RSNP.0.P.B_meme_format.meme
Transfac format	ANDR.H12RSNP.0.P.B_transfac_format.txt
Homer format	ANDR.H12RSNP.0.P.B_homer_format_0.001.txt ANDR.H12RSNP.0.P.B_homer_format_0.0005.txt ANDR.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	127.0	0.0	93.0	17.0
02	2.0	5.0	210.0	20.0
03	95.0	29.0	35.0	78.0
04	220.0	12.0	1.0	4.0
05	0.0	234.0	3.0	0.0
06	191.0	1.0	20.0	25.0
07	25.0	65.0	46.0	101.0
08	14.0	33.0	54.0	136.0
09	14.0	88.0	90.0	45.0
10	15.0	13.0	5.0	204.0
11	3.0	1.0	232.0	1.0
12	3.0	7.0	2.0	225.0
13	32.0	24.0	26.0	155.0
14	4.0	225.0	0.0	8.0
15	10.0	105.0	2.0	120.0
16	34.0	73.0	30.0	100.0
17	34.0	39.0	58.0	106.0
18	33.0	53.0	68.0	83.0
19	43.0	89.0	34.0	71.0

PFM

	A	C	G	T
01	0.536	0.0	0.392	0.072
02	0.008	0.021	0.886	0.084
03	0.401	0.122	0.148	0.329
04	0.928	0.051	0.004	0.017
05	0.0	0.987	0.013	0.0
06	0.806	0.004	0.084	0.105
07	0.105	0.274	0.194	0.426
08	0.059	0.139	0.228	0.574
09	0.059	0.371	0.38	0.19
10	0.063	0.055	0.021	0.861
11	0.013	0.004	0.979	0.004
12	0.013	0.03	0.008	0.949
13	0.135	0.101	0.11	0.654
14	0.017	0.949	0.0	0.034
15	0.042	0.443	0.008	0.506
16	0.143	0.308	0.127	0.422
17	0.143	0.165	0.245	0.447
18	0.139	0.224	0.287	0.35
19	0.181	0.376	0.143	0.3

PWM

	A	C	G	T
01	0.75	-3.792	0.443	-1.194
02	-2.891	-2.253	1.249	-1.043
03	0.464	-0.691	-0.511	0.27
04	1.295	-1.512	-3.243	-2.424
05	-3.792	1.357	-2.63	-3.792
06	1.155	-3.243	-1.043	-0.832
07	-0.832	0.091	-0.247	0.524
08	-1.372	-0.567	-0.091	0.818
09	-1.372	0.388	0.41	-0.268
10	-1.309	-1.44	-2.253	1.22
11	-2.63	-3.243	1.348	-3.243
12	-2.63	-1.98	-2.891	1.318
13	-0.597	-0.871	-0.795	0.948
14	-2.424	1.318	-3.792	-1.867
15	-1.674	0.562	-2.891	0.694
16	-0.539	0.204	-0.659	0.514
17	-0.539	-0.407	-0.021	0.572
18	-0.567	-0.109	0.135	0.331
19	-0.312	0.399	-0.539	0.177

Standard thresholds

P-value	Threshold
0.001	3.05791
0.0005	4.19041
0.0001	6.56721