ANDR.H12INVIVO.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12INVIVO.2.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	19
Consensus	WKThYYhnnnTRTTTRYhb
GC content	38.12%
Information content (bits; total / per base)	12.611 / 0.664
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.757	0.888	0.67	0.849	0.801	0.917	3.316	5.428	81.013	435.796
Mouse	20 (35)	0.562	0.78	0.436	0.773	0.629	0.829	1.967	4.77	14.824	109.071

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.539	0.522	0.532	0.519	0.524	0.515
Non-Methyl HT-SELEX, 3 experiments	best	0.562	0.541	0.542	0.529	0.529	0.521

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.513	11.758	0.051	0.021

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12INVIVO.2.P.B.pcm
PWM	ANDR.H12INVIVO.2.P.B.pwm
PFM	ANDR.H12INVIVO.2.P.B.pfm
Alignment	ANDR.H12INVIVO.2.P.B.words.tsv
Threshold to P-value map	ANDR.H12INVIVO.2.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12INVIVO.2.P.B_jaspar_format.txt
MEME format	ANDR.H12INVIVO.2.P.B_meme_format.meme
Transfac format	ANDR.H12INVIVO.2.P.B_transfac_format.txt
Homer format	ANDR.H12INVIVO.2.P.B_homer_format_0.001.txt ANDR.H12INVIVO.2.P.B_homer_format_0.0005.txt ANDR.H12INVIVO.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	156.0	62.0	79.0	701.0
02	68.0	80.0	757.0	93.0
03	93.0	61.0	40.0	804.0
04	216.0	202.0	163.0	417.0
05	77.0	763.0	32.0	126.0
06	103.0	387.0	22.0	486.0
07	228.0	194.0	166.0	410.0
08	207.0	214.0	250.0	327.0
09	196.0	180.0	263.0	359.0
10	183.0	314.0	158.0	343.0
11	78.0	11.0	30.0	879.0
12	222.0	33.0	737.0	6.0
13	13.0	37.0	12.0	936.0
14	17.0	15.0	121.0	845.0
15	17.0	9.0	129.0	843.0
16	568.0	24.0	372.0	34.0
17	65.0	649.0	28.0	256.0
18	336.0	186.0	39.0	437.0
19	97.0	270.0	139.0	492.0

PFM

	A	C	G	T
01	0.156	0.062	0.079	0.702
02	0.068	0.08	0.759	0.093
03	0.093	0.061	0.04	0.806
04	0.216	0.202	0.163	0.418
05	0.077	0.765	0.032	0.126
06	0.103	0.388	0.022	0.487
07	0.228	0.194	0.166	0.411
08	0.207	0.214	0.251	0.328
09	0.196	0.18	0.264	0.36
10	0.183	0.315	0.158	0.344
11	0.078	0.011	0.03	0.881
12	0.222	0.033	0.738	0.006
13	0.013	0.037	0.012	0.938
14	0.017	0.015	0.121	0.847
15	0.017	0.009	0.129	0.845
16	0.569	0.024	0.373	0.034
17	0.065	0.65	0.028	0.257
18	0.337	0.186	0.039	0.438
19	0.097	0.271	0.139	0.493

PWM

	A	C	G	T
01	-0.465	-1.372	-1.135	1.029
02	-1.282	-1.123	1.105	-0.975
03	-0.975	-1.388	-1.795	1.165
04	-0.143	-0.21	-0.422	0.511
05	-1.16	1.113	-2.008	-0.676
06	-0.875	0.437	-2.36	0.663
07	-0.089	-0.25	-0.404	0.494
08	-0.185	-0.152	0.002	0.269
09	-0.239	-0.324	0.052	0.362
10	-0.307	0.229	-0.453	0.316
11	-1.148	-2.983	-2.069	1.254
12	-0.116	-1.979	1.079	-3.482
13	-2.837	-1.87	-2.907	1.317
14	-2.596	-2.709	-0.716	1.215
15	-2.596	-3.154	-0.653	1.213
16	0.819	-2.279	0.397	-1.95
17	-1.326	0.952	-2.134	0.026
18	0.296	-0.291	-1.819	0.558
19	-0.934	0.078	-0.58	0.676

Standard thresholds

P-value	Threshold
0.001	4.07506
0.0005	5.02141
0.0001	7.00446