ANDR.H12INVITRO.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12INVITRO.2.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	19
Consensus	dRKhMYhbdnKRTTYvhhb
GC content	37.72%
Information content (bits; total / per base)	10.753 / 0.566
Data sources	ChIP-Seq
Aligned words	801

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.727	0.864	0.618	0.817	0.795	0.915	2.969	4.927	73.602	409.721
Mouse	20 (35)	0.589	0.77	0.434	0.745	0.649	0.807	1.834	4.154	26.456	113.119

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.566	0.537	0.551	0.531	0.534	0.523
Non-Methyl HT-SELEX, 3 experiments	best	0.791	0.714	0.75	0.684	0.692	0.646

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.472	10.427	0.045	0.02

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12INVITRO.2.P.B.pcm
PWM	ANDR.H12INVITRO.2.P.B.pwm
PFM	ANDR.H12INVITRO.2.P.B.pfm
Alignment	ANDR.H12INVITRO.2.P.B.words.tsv
Threshold to P-value map	ANDR.H12INVITRO.2.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12INVITRO.2.P.B_jaspar_format.txt
MEME format	ANDR.H12INVITRO.2.P.B_meme_format.meme
Transfac format	ANDR.H12INVITRO.2.P.B_transfac_format.txt
Homer format	ANDR.H12INVITRO.2.P.B_homer_format_0.001.txt ANDR.H12INVITRO.2.P.B_homer_format_0.0005.txt ANDR.H12INVITRO.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	126.0	87.0	139.0	449.0
02	164.0	38.0	542.0	57.0
03	70.0	22.0	92.0	617.0
04	176.0	111.0	106.0	408.0
05	139.0	579.0	15.0	68.0
06	54.0	442.0	8.0	297.0
07	315.0	97.0	81.0	308.0
08	104.0	140.0	190.0	367.0
09	162.0	126.0	187.0	326.0
10	126.0	250.0	149.0	276.0
11	64.0	37.0	69.0	631.0
12	236.0	22.0	535.0	8.0
13	19.0	19.0	7.0	756.0
14	17.0	18.0	82.0	684.0
15	11.0	187.0	51.0	552.0
16	331.0	138.0	235.0	97.0
17	139.0	412.0	47.0	203.0
18	200.0	137.0	46.0	418.0
19	76.0	169.0	129.0	427.0

PFM

	A	C	G	T
01	0.157	0.109	0.174	0.561
02	0.205	0.047	0.677	0.071
03	0.087	0.027	0.115	0.77
04	0.22	0.139	0.132	0.509
05	0.174	0.723	0.019	0.085
06	0.067	0.552	0.01	0.371
07	0.393	0.121	0.101	0.385
08	0.13	0.175	0.237	0.458
09	0.202	0.157	0.233	0.407
10	0.157	0.312	0.186	0.345
11	0.08	0.046	0.086	0.788
12	0.295	0.027	0.668	0.01
13	0.024	0.024	0.009	0.944
14	0.021	0.022	0.102	0.854
15	0.014	0.233	0.064	0.689
16	0.413	0.172	0.293	0.121
17	0.174	0.514	0.059	0.253
18	0.25	0.171	0.057	0.522
19	0.095	0.211	0.161	0.533

PWM

	A	C	G	T
01	-0.458	-0.823	-0.361	0.803
02	-0.198	-1.627	0.99	-1.236
03	-1.036	-2.144	-0.768	1.12
04	-0.128	-0.583	-0.629	0.707
05	-0.361	1.056	-2.494	-1.064
06	-1.288	0.787	-3.039	0.391
07	0.45	-0.716	-0.893	0.428
08	-0.648	-0.354	-0.052	0.602
09	-0.21	-0.458	-0.068	0.484
10	-0.458	0.22	-0.293	0.319
11	-1.123	-1.653	-1.05	1.142
12	0.163	-2.144	0.978	-3.039
13	-2.279	-2.279	-3.148	1.322
14	-2.381	-2.329	-0.881	1.223
15	-2.769	-0.068	-1.344	1.009
16	0.499	-0.369	0.159	-0.716
17	-0.361	0.717	-1.423	0.014
18	-0.001	-0.376	-1.444	0.732
19	-0.955	-0.168	-0.435	0.753

Standard thresholds

P-value	Threshold
0.001	4.56141
0.0005	5.39541
0.0001	7.13346