ANDR.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12INVITRO.0.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	RGdACAnAvTGTbCY
GC content	48.85%
Information content (bits; total / per base)	16.073 / 1.072
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.849	0.982	0.788	0.976	0.822	0.986	3.185	6.643	197.056	543.886
Mouse	20 (35)	0.924	0.983	0.881	0.965	0.928	0.988	4.706	6.637	400.201	628.201

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.684	0.704	0.575	0.601	0.533	0.555
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.994	0.992	0.914	0.916

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.159	1.939	0.028	0.014

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12INVITRO.0.P.B.pcm
PWM	ANDR.H12INVITRO.0.P.B.pwm
PFM	ANDR.H12INVITRO.0.P.B.pfm
Alignment	ANDR.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ANDR.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ANDR.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ANDR.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ANDR.H12INVITRO.0.P.B_homer_format_0.001.txt ANDR.H12INVITRO.0.P.B_homer_format_0.0005.txt ANDR.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	459.0	7.0	473.0	57.0
02	40.0	5.0	917.0	34.0
03	444.0	137.0	272.0	143.0
04	973.0	10.0	7.0	6.0
05	1.0	982.0	10.0	3.0
06	903.0	5.0	41.0	47.0
07	209.0	286.0	354.0	147.0
08	658.0	0.0	338.0	0.0
09	378.0	231.0	314.0	73.0
10	72.0	78.0	17.0	829.0
11	8.0	8.0	979.0	1.0
12	8.0	14.0	3.0	971.0
13	134.0	242.0	153.0	467.0
14	18.0	954.0	1.0	23.0
15	75.0	448.0	12.0	461.0

PFM

	A	C	G	T
01	0.461	0.007	0.475	0.057
02	0.04	0.005	0.921	0.034
03	0.446	0.138	0.273	0.144
04	0.977	0.01	0.007	0.006
05	0.001	0.986	0.01	0.003
06	0.907	0.005	0.041	0.047
07	0.21	0.287	0.355	0.148
08	0.661	0.0	0.339	0.0
09	0.38	0.232	0.315	0.073
10	0.072	0.078	0.017	0.832
11	0.008	0.008	0.983	0.001
12	0.008	0.014	0.003	0.975
13	0.135	0.243	0.154	0.469
14	0.018	0.958	0.001	0.023
15	0.075	0.45	0.012	0.463

PWM

	A	C	G	T
01	0.608	-3.358	0.638	-1.451
02	-1.793	-3.618	1.299	-1.948
03	0.575	-0.592	0.088	-0.55
04	1.358	-3.063	-3.358	-3.48
05	-4.522	1.367	-3.063	-3.971
06	1.283	-3.618	-1.77	-1.638
07	-0.174	0.138	0.35	-0.522
08	0.967	-4.979	0.304	-4.979
09	0.415	-0.074	0.231	-1.211
10	-1.224	-1.146	-2.594	1.198
11	-3.25	-3.25	1.364	-4.522
12	-3.25	-2.769	-3.971	1.356
13	-0.614	-0.028	-0.483	0.626
14	-2.542	1.338	-4.522	-2.317
15	-1.184	0.584	-2.905	0.613

Standard thresholds

P-value	Threshold
0.001	2.06241
0.0005	3.38661
0.0001	6.11571