ANDR.H12CORE.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12CORE.2.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	19
Consensus	WKYhYhbnnnTRTTTRYhb
GC content	40.77%
Information content (bits; total / per base)	11.495 / 0.605
Data sources	ChIP-Seq
Aligned words	1004

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.757	0.88	0.665	0.839	0.803	0.909	3.255	5.246	75.678	413.131
Mouse	20 (35)	0.566	0.78	0.432	0.774	0.656	0.83	2.023	4.797	14.31	106.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.542	0.525	0.532	0.519	0.524	0.515
Non-Methyl HT-SELEX, 3 experiments	best	0.569	0.546	0.547	0.532	0.533	0.523

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.529	12.345	0.052	0.022

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12CORE.2.P.B.pcm
PWM	ANDR.H12CORE.2.P.B.pwm
PFM	ANDR.H12CORE.2.P.B.pfm
Alignment	ANDR.H12CORE.2.P.B.words.tsv
Threshold to P-value map	ANDR.H12CORE.2.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12CORE.2.P.B_jaspar_format.txt
MEME format	ANDR.H12CORE.2.P.B_meme_format.meme
Transfac format	ANDR.H12CORE.2.P.B_transfac_format.txt
Homer format	ANDR.H12CORE.2.P.B_homer_format_0.001.txt ANDR.H12CORE.2.P.B_homer_format_0.0005.txt ANDR.H12CORE.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	145.0	79.0	110.0	670.0
02	71.0	78.0	755.0	100.0
03	88.25	100.25	53.25	762.25
04	177.25	200.25	150.25	476.25
05	74.25	740.25	37.25	152.25
06	104.25	386.25	50.25	463.25
07	174.25	214.25	213.25	402.25
08	184.25	225.25	249.25	345.25
09	202.25	210.25	266.25	325.25
10	198.25	316.25	153.25	336.25
11	62.25	21.25	33.25	887.25
12	183.25	52.25	759.25	9.25
13	33.25	48.25	17.25	905.25
14	17.25	25.25	144.25	817.25
15	20.25	14.25	108.25	861.25
16	390.25	68.25	504.25	41.25
17	64.25	643.25	41.25	255.25
18	328.25	183.25	65.25	427.25
19	84.25	288.25	172.25	459.25

PFM

	A	C	G	T
01	0.144	0.079	0.11	0.667
02	0.071	0.078	0.752	0.1
03	0.088	0.1	0.053	0.759
04	0.177	0.199	0.15	0.474
05	0.074	0.737	0.037	0.152
06	0.104	0.385	0.05	0.461
07	0.174	0.213	0.212	0.401
08	0.184	0.224	0.248	0.344
09	0.201	0.209	0.265	0.324
10	0.197	0.315	0.153	0.335
11	0.062	0.021	0.033	0.884
12	0.183	0.052	0.756	0.009
13	0.033	0.048	0.017	0.902
14	0.017	0.025	0.144	0.814
15	0.02	0.014	0.108	0.858
16	0.389	0.068	0.502	0.041
17	0.064	0.641	0.041	0.254
18	0.327	0.183	0.065	0.426
19	0.084	0.287	0.172	0.457

PWM

	A	C	G	T
01	-0.544	-1.141	-0.816	0.978
02	-1.246	-1.154	1.097	-0.91
03	-1.033	-0.908	-1.525	1.106
04	-0.345	-0.224	-0.509	0.637
05	-1.202	1.077	-1.869	-0.496
06	-0.869	0.429	-1.581	0.61
07	-0.362	-0.157	-0.162	0.469
08	-0.307	-0.107	-0.007	0.317
09	-0.214	-0.176	0.059	0.258
10	-0.234	0.23	-0.489	0.291
11	-1.374	-2.398	-1.978	1.258
12	-0.312	-1.544	1.102	-3.136
13	-1.978	-1.621	-2.589	1.278
14	-2.589	-2.237	-0.549	1.176
15	-2.442	-2.761	-0.832	1.228
16	0.439	-1.284	0.694	-1.772
17	-1.343	0.937	-1.772	0.017
18	0.267	-0.312	-1.328	0.529
19	-1.078	0.137	-0.373	0.601

Standard thresholds

P-value	Threshold
0.001	4.37516
0.0005	5.24491
0.0001	7.07456