ANDR.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ANDR.H12CORE.0.P.B
Gene (human)	AR (GeneCards)
Gene synonyms (human)	DHTR, NR3C4
Gene (mouse)	Ar
Gene synonyms (mouse)	Nr3c4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	dKnWCWbnvTGTWCYbd
GC content	47.22%
Information content (bits; total / per base)	13.753 / 0.809
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	237 (413)	0.863	0.978	0.793	0.966	0.832	0.977	3.209	6.274	204.495	542.268
Mouse	20 (35)	0.923	0.979	0.876	0.956	0.921	0.983	4.503	5.967	389.62	611.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.694	0.708	0.586	0.606	0.539	0.559
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.998	0.992	0.99	0.918	0.917

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.154	1.832	0.032	0.005

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.4
HGNC	HGNC:644
MGI	MGI:88064
EntrezGene (human)	GeneID:367 (SSTAR profile)
EntrezGene (mouse)	GeneID:11835 (SSTAR profile)
UniProt ID (human)	ANDR_HUMAN
UniProt ID (mouse)	ANDR_MOUSE
UniProt AC (human)	P10275 (TFClass)
UniProt AC (mouse)	P19091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	237 human, 20 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	ANDR.H12CORE.0.P.B.pcm
PWM	ANDR.H12CORE.0.P.B.pwm
PFM	ANDR.H12CORE.0.P.B.pfm
Alignment	ANDR.H12CORE.0.P.B.words.tsv
Threshold to P-value map	ANDR.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	ANDR.H12CORE.0.P.B_jaspar_format.txt
MEME format	ANDR.H12CORE.0.P.B_meme_format.meme
Transfac format	ANDR.H12CORE.0.P.B_transfac_format.txt
Homer format	ANDR.H12CORE.0.P.B_homer_format_0.001.txt ANDR.H12CORE.0.P.B_homer_format_0.0005.txt ANDR.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	416.0	18.0	334.0	232.0
02	120.0	18.0	732.0	130.0
03	273.0	250.0	248.0	229.0
04	776.0	51.0	66.0	107.0
05	4.0	948.0	26.0	22.0
06	669.0	30.0	79.0	222.0
07	121.0	266.0	340.0	273.0
08	309.0	201.0	228.0	262.0
09	264.0	340.0	281.0	115.0
10	21.0	19.0	3.0	957.0
11	2.0	2.0	995.0	1.0
12	8.0	3.0	0.0	989.0
13	126.0	91.0	94.0	689.0
14	7.0	979.0	0.0	14.0
15	4.0	511.0	2.0	483.0
16	162.0	252.0	183.0	403.0
17	167.0	128.0	310.0	395.0

PFM

	A	C	G	T
01	0.416	0.018	0.334	0.232
02	0.12	0.018	0.732	0.13
03	0.273	0.25	0.248	0.229
04	0.776	0.051	0.066	0.107
05	0.004	0.948	0.026	0.022
06	0.669	0.03	0.079	0.222
07	0.121	0.266	0.34	0.273
08	0.309	0.201	0.228	0.262
09	0.264	0.34	0.281	0.115
10	0.021	0.019	0.003	0.957
11	0.002	0.002	0.995	0.001
12	0.008	0.003	0.0	0.989
13	0.126	0.091	0.094	0.689
14	0.007	0.979	0.0	0.014
15	0.004	0.511	0.002	0.483
16	0.162	0.252	0.183	0.403
17	0.167	0.128	0.31	0.395

PWM

	A	C	G	T
01	0.506	-2.546	0.288	-0.074
02	-0.727	-2.546	1.07	-0.648
03	0.087	0.0	-0.008	-0.087
04	1.128	-1.563	-1.313	-0.84
05	-3.783	1.328	-2.206	-2.362
06	0.98	-2.071	-1.137	-0.118
07	-0.718	0.062	0.306	0.087
08	0.211	-0.216	-0.091	0.047
09	0.054	0.306	0.116	-0.769
10	-2.405	-2.497	-3.975	1.337
11	-4.213	-4.213	1.376	-4.525
12	-3.253	-3.975	-4.982	1.37
13	-0.678	-0.999	-0.967	1.009
14	-3.362	1.36	-4.982	-2.773
15	-3.783	0.711	-4.213	0.655
16	-0.43	0.008	-0.309	0.475
17	-0.4	-0.663	0.214	0.455

Standard thresholds

P-value	Threshold
0.001	3.30296
0.0005	4.48506
0.0001	6.92891