ALX4.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ALX4.H12INVITRO.0.S.B
Gene (human)	ALX4 (GeneCards)
Gene synonyms (human)	KIAA1788
Gene (mouse)	Alx4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	20
Consensus	vvbTAATTRRATTAvbnnnn
GC content	32.13%
Information content (bits; total / per base)	17.273 / 0.864
Data sources	HT-SELEX
Aligned words	6332

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.997	0.995	0.988	0.984	0.9	0.902
Overall, 6 experiments	best	1.0	0.999	0.999	0.999	0.997	0.996
Methyl HT-SELEX, 1 experiments	median	0.946	0.911	0.917	0.877	0.871	0.829
Methyl HT-SELEX, 1 experiments	best	0.946	0.911	0.917	0.877	0.871	0.829
Non-Methyl HT-SELEX, 5 experiments	median	0.997	0.996	0.992	0.988	0.91	0.914
Non-Methyl HT-SELEX, 5 experiments	best	1.0	0.999	0.999	0.999	0.997	0.996

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	ALX {3.1.3.1} (TFClass)
TFClass ID	TFClass: 3.1.3.1.3
HGNC	HGNC:450
MGI	MGI:108359
EntrezGene (human)	GeneID:60529 (SSTAR profile)
EntrezGene (mouse)	GeneID:11695 (SSTAR profile)
UniProt ID (human)	ALX4_HUMAN
UniProt ID (mouse)	ALX4_MOUSE
UniProt AC (human)	Q9H161 (TFClass)
UniProt AC (mouse)	O35137 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	ALX4.H12INVITRO.0.S.B.pcm
PWM	ALX4.H12INVITRO.0.S.B.pwm
PFM	ALX4.H12INVITRO.0.S.B.pfm
Alignment	ALX4.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	ALX4.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	ALX4.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	ALX4.H12INVITRO.0.S.B_meme_format.meme
Transfac format	ALX4.H12INVITRO.0.S.B_transfac_format.txt
Homer format	ALX4.H12INVITRO.0.S.B_homer_format_0.001.txt ALX4.H12INVITRO.0.S.B_homer_format_0.0005.txt ALX4.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1397.25	1257.25	2688.25	989.25
02	1259.5	1054.5	3185.5	832.5
03	380.0	2454.0	1817.0	1681.0
04	100.0	176.0	16.0	6040.0
05	6191.0	2.0	137.0	2.0
06	6332.0	0.0	0.0	0.0
07	0.0	6.0	0.0	6326.0
08	0.0	951.0	42.0	5339.0
09	3814.0	418.0	1116.0	984.0
10	2823.0	230.0	3279.0	0.0
11	5551.0	96.0	426.0	259.0
12	4.0	104.0	55.0	6169.0
13	215.0	314.0	40.0	5763.0
14	5980.0	44.0	177.0	131.0
15	2252.0	1155.0	2410.0	515.0
16	949.0	1646.0	1270.0	2467.0
17	964.0	1471.0	1608.0	2289.0
18	1514.0	2254.0	1409.0	1155.0
19	1351.0	2362.0	1411.0	1208.0
20	1310.25	2205.25	1401.25	1415.25

PFM

	A	C	G	T
01	0.221	0.199	0.425	0.156
02	0.199	0.167	0.503	0.131
03	0.06	0.388	0.287	0.265
04	0.016	0.028	0.003	0.954
05	0.978	0.0	0.022	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.001	0.0	0.999
08	0.0	0.15	0.007	0.843
09	0.602	0.066	0.176	0.155
10	0.446	0.036	0.518	0.0
11	0.877	0.015	0.067	0.041
12	0.001	0.016	0.009	0.974
13	0.034	0.05	0.006	0.91
14	0.944	0.007	0.028	0.021
15	0.356	0.182	0.381	0.081
16	0.15	0.26	0.201	0.39
17	0.152	0.232	0.254	0.361
18	0.239	0.356	0.223	0.182
19	0.213	0.373	0.223	0.191
20	0.207	0.348	0.221	0.224

PWM

	A	C	G	T
01	-0.125	-0.23	0.529	-0.469
02	-0.228	-0.406	0.699	-0.641
03	-1.423	0.438	0.138	0.06
04	-2.742	-2.186	-4.468	1.338
05	1.363	-5.936	-2.433	-5.936
06	1.385	-6.585	-6.585	-6.585
07	-6.585	-5.266	-6.585	1.384
08	-6.585	-0.509	-3.58	1.215
09	0.879	-1.328	-0.349	-0.475
10	0.578	-1.921	0.728	-6.585
11	1.254	-2.782	-1.309	-1.803
12	-5.546	-2.703	-3.322	1.359
13	-1.988	-1.612	-3.626	1.291
14	1.328	-3.536	-2.18	-2.477
15	0.352	-0.315	0.42	-1.12
16	-0.511	0.039	-0.22	0.443
17	-0.495	-0.073	0.016	0.368
18	-0.045	0.353	-0.116	-0.315
19	-0.158	0.4	-0.115	-0.27
20	-0.189	0.331	-0.122	-0.112

Standard thresholds

P-value	Threshold
0.001	0.57776
0.0005	2.15766
0.0001	5.40806