Motif | ALX1.H12CORE.0.SM.B |
Gene (human) | ALX1 (GeneCards) |
Gene synonyms (human) | CART1 |
Gene (mouse) | Alx1 |
Gene synonyms (mouse) | Cart1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | ALX1.H12CORE.0.SM.B |
Gene (human) | ALX1 (GeneCards) |
Gene synonyms (human) | CART1 |
Gene (mouse) | Alx1 |
Gene synonyms (mouse) | Cart1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 20 |
Consensus | nvbTAATTRRRTTAvnnnnn |
GC content | 33.1% |
Information content (bits; total / per base) | 15.666 / 0.783 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 7125 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.998 | 0.996 | 0.912 | 0.923 | 0.821 | 0.835 |
best | 1.0 | 0.999 | 0.996 | 0.994 | 0.984 | 0.98 | |
Methyl HT-SELEX, 1 experiments | median | 1.0 | 0.999 | 0.825 | 0.857 | 0.624 | 0.696 |
best | 1.0 | 0.999 | 0.825 | 0.857 | 0.624 | 0.696 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.997 | 0.995 | 0.993 | 0.99 | 0.966 | 0.96 |
best | 0.998 | 0.997 | 0.996 | 0.994 | 0.984 | 0.98 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.776 | 0.441 | 0.72 | 0.45 |
batch 2 | 0.816 | 0.718 | 0.756 | 0.516 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | ALX {3.1.3.1} (TFClass) |
TFClass ID | TFClass: 3.1.3.1.1 |
HGNC | HGNC:1494 |
MGI | MGI:104621 |
EntrezGene (human) | GeneID:8092 (SSTAR profile) |
EntrezGene (mouse) | GeneID:216285 (SSTAR profile) |
UniProt ID (human) | ALX1_HUMAN |
UniProt ID (mouse) | ALX1_MOUSE |
UniProt AC (human) | Q15699 (TFClass) |
UniProt AC (mouse) | Q8C8B0 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | ALX1.H12CORE.0.SM.B.pcm |
PWM | ALX1.H12CORE.0.SM.B.pwm |
PFM | ALX1.H12CORE.0.SM.B.pfm |
Alignment | ALX1.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | ALX1.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | ALX1.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | ALX1.H12CORE.0.SM.B_meme_format.meme |
Transfac format | ALX1.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1630.0 | 2253.0 | 2148.0 | 1094.0 |
02 | 1512.5 | 1762.5 | 2838.5 | 1011.5 |
03 | 495.0 | 3206.0 | 1623.0 | 1801.0 |
04 | 152.0 | 237.0 | 23.0 | 6713.0 |
05 | 6951.0 | 2.0 | 162.0 | 10.0 |
06 | 7125.0 | 0.0 | 0.0 | 0.0 |
07 | 2.0 | 80.0 | 3.0 | 7040.0 |
08 | 0.0 | 1149.0 | 90.0 | 5886.0 |
09 | 4453.0 | 407.0 | 1192.0 | 1073.0 |
10 | 3215.0 | 431.0 | 3468.0 | 11.0 |
11 | 5587.0 | 338.0 | 857.0 | 343.0 |
12 | 58.0 | 188.0 | 152.0 | 6727.0 |
13 | 288.0 | 506.0 | 125.0 | 6206.0 |
14 | 6316.0 | 136.0 | 351.0 | 322.0 |
15 | 2596.0 | 1338.0 | 2485.0 | 706.0 |
16 | 1045.0 | 2110.0 | 1453.0 | 2517.0 |
17 | 1174.0 | 1708.0 | 1879.0 | 2364.0 |
18 | 1574.0 | 2058.0 | 2096.0 | 1397.0 |
19 | 1534.5 | 2061.5 | 2119.5 | 1409.5 |
20 | 1451.0 | 2047.0 | 2090.0 | 1537.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.229 | 0.316 | 0.301 | 0.154 |
02 | 0.212 | 0.247 | 0.398 | 0.142 |
03 | 0.069 | 0.45 | 0.228 | 0.253 |
04 | 0.021 | 0.033 | 0.003 | 0.942 |
05 | 0.976 | 0.0 | 0.023 | 0.001 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.011 | 0.0 | 0.988 |
08 | 0.0 | 0.161 | 0.013 | 0.826 |
09 | 0.625 | 0.057 | 0.167 | 0.151 |
10 | 0.451 | 0.06 | 0.487 | 0.002 |
11 | 0.784 | 0.047 | 0.12 | 0.048 |
12 | 0.008 | 0.026 | 0.021 | 0.944 |
13 | 0.04 | 0.071 | 0.018 | 0.871 |
14 | 0.886 | 0.019 | 0.049 | 0.045 |
15 | 0.364 | 0.188 | 0.349 | 0.099 |
16 | 0.147 | 0.296 | 0.204 | 0.353 |
17 | 0.165 | 0.24 | 0.264 | 0.332 |
18 | 0.221 | 0.289 | 0.294 | 0.196 |
19 | 0.215 | 0.289 | 0.297 | 0.198 |
20 | 0.204 | 0.287 | 0.293 | 0.216 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.089 | 0.235 | 0.187 | -0.487 |
02 | -0.163 | -0.011 | 0.465 | -0.565 |
03 | -1.277 | 0.587 | -0.093 | 0.011 |
04 | -2.448 | -2.009 | -4.259 | 1.326 |
05 | 1.361 | -6.047 | -2.385 | -4.983 |
06 | 1.385 | -6.69 | -6.69 | -6.69 |
07 | -6.047 | -3.077 | -5.834 | 1.373 |
08 | -6.69 | -0.438 | -2.962 | 1.194 |
09 | 0.916 | -1.472 | -0.401 | -0.506 |
10 | 0.59 | -1.415 | 0.666 | -4.905 |
11 | 1.142 | -1.657 | -0.73 | -1.642 |
12 | -3.388 | -2.238 | -2.448 | 1.328 |
13 | -1.816 | -1.255 | -2.64 | 1.247 |
14 | 1.265 | -2.557 | -1.619 | -1.705 |
15 | 0.376 | -0.286 | 0.333 | -0.924 |
16 | -0.532 | 0.169 | -0.203 | 0.345 |
17 | -0.416 | -0.042 | 0.053 | 0.283 |
18 | -0.124 | 0.144 | 0.163 | -0.243 |
19 | -0.149 | 0.146 | 0.174 | -0.234 |
20 | -0.205 | 0.139 | 0.16 | -0.147 |
P-value | Threshold |
---|---|
0.001 | 2.09491 |
0.0005 | 3.46966 |
0.0001 | 6.26466 |