MotifALX1.H12CORE.0.SM.B
Gene (human)ALX1
(GeneCards)
Gene synonyms (human)CART1
Gene (mouse)Alx1
Gene synonyms (mouse)Cart1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length20
ConsensusnvbTAATTRRRTTAvnnnnn
GC content33.1%
Information content (bits; total / per base)15.666 / 0.783
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7125

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.998 0.996 0.912 0.923 0.821 0.835
best 1.0 0.999 0.996 0.994 0.984 0.98
Methyl HT-SELEX, 1 experiments median 1.0 0.999 0.825 0.857 0.624 0.696
best 1.0 0.999 0.825 0.857 0.624 0.696
Non-Methyl HT-SELEX, 3 experiments median 0.997 0.995 0.993 0.99 0.966 0.96
best 0.998 0.997 0.996 0.994 0.984 0.98

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.776 0.441 0.72 0.45
batch 2 0.816 0.718 0.756 0.516
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyALX {3.1.3.1} (TFClass)
TFClass IDTFClass: 3.1.3.1.1
HGNCHGNC:1494
MGIMGI:104621
EntrezGene (human)GeneID:8092
(SSTAR profile)
EntrezGene (mouse)GeneID:216285
(SSTAR profile)
UniProt ID (human)ALX1_HUMAN
UniProt ID (mouse)ALX1_MOUSE
UniProt AC (human)Q15699
(TFClass)
UniProt AC (mouse)Q8C8B0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011630.02253.02148.01094.0
021512.51762.52838.51011.5
03495.03206.01623.01801.0
04152.0237.023.06713.0
056951.02.0162.010.0
067125.00.00.00.0
072.080.03.07040.0
080.01149.090.05886.0
094453.0407.01192.01073.0
103215.0431.03468.011.0
115587.0338.0857.0343.0
1258.0188.0152.06727.0
13288.0506.0125.06206.0
146316.0136.0351.0322.0
152596.01338.02485.0706.0
161045.02110.01453.02517.0
171174.01708.01879.02364.0
181574.02058.02096.01397.0
191534.52061.52119.51409.5
201451.02047.02090.01537.0
PFM
ACGT
010.2290.3160.3010.154
020.2120.2470.3980.142
030.0690.450.2280.253
040.0210.0330.0030.942
050.9760.00.0230.001
061.00.00.00.0
070.00.0110.00.988
080.00.1610.0130.826
090.6250.0570.1670.151
100.4510.060.4870.002
110.7840.0470.120.048
120.0080.0260.0210.944
130.040.0710.0180.871
140.8860.0190.0490.045
150.3640.1880.3490.099
160.1470.2960.2040.353
170.1650.240.2640.332
180.2210.2890.2940.196
190.2150.2890.2970.198
200.2040.2870.2930.216
PWM
ACGT
01-0.0890.2350.187-0.487
02-0.163-0.0110.465-0.565
03-1.2770.587-0.0930.011
04-2.448-2.009-4.2591.326
051.361-6.047-2.385-4.983
061.385-6.69-6.69-6.69
07-6.047-3.077-5.8341.373
08-6.69-0.438-2.9621.194
090.916-1.472-0.401-0.506
100.59-1.4150.666-4.905
111.142-1.657-0.73-1.642
12-3.388-2.238-2.4481.328
13-1.816-1.255-2.641.247
141.265-2.557-1.619-1.705
150.376-0.2860.333-0.924
16-0.5320.169-0.2030.345
17-0.416-0.0420.0530.283
18-0.1240.1440.163-0.243
19-0.1490.1460.174-0.234
20-0.2050.1390.16-0.147
Standard thresholds
P-value Threshold
0.001 2.09491
0.0005 3.46966
0.0001 6.26466